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Blood Cancer Clinical Trials

A listing of Blood Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (1167) clinical trials

Biological Therapy and Combination Chemotherapy in Treating Patients With Lymphomatoid Granulomatosis

OBJECTIVES: - Determine the long-term efficacy of interferon alfa in patients with lymphomatoid granulomatosis. - Determine the long-term efficacy of etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab in patients with grade III lymphomatoid granulomatosis OR in patients who fail interferon therapy. - Determine the response in patients treated with these ...

Phase

Evaluation of Patients Who Have Skin Diseases

OBJECTIVES: Primary - Determine the natural history of selected dermatologic or systemic diseases with cutaneous manifestations. - Provide clinical material to fulfill the educational mission of the Dermatology Branch. Secondary - Screen patients for inclusion in other protocols. - Assist the treating physicians with determining the diagnosis and appropriate medical ...

Phase N/A

Radiolabeled Monoclonal Antibody Therapy in Treating Adult Patients Who Have Recurrent Hodgkin's Lymphoma or Non-Hodgkin's Lymphoma

OBJECTIVES: - Assess the toxicity and therapeutic efficacy of yttrium Y 90 radiolabeled humanized anti-Tac (HAT) monoclonal antibody in patients with Tac expressing hematologic malignancies. - Define the pharmacokinetics of indium In 111 and yttrium Y 90 HAT monoclonal antibodies. OUTLINE: This is a dose-escalation study. Patients are given yttrium ...

Phase

Chemotherapy Followed by Allogeneic Stem Cell Transplantation in Treating Children With Hematologic Cancer

OBJECTIVES: Primary - Determine the efficacy and safety of non-myeloablative chemotherapy in facilitating donor engraftment after allogeneic stem cell transplantation with G-CSF mobilized peripheral blood stem cells in patients with pediatric hematopoietic malignancies. (Cohort 1) (closed to accrual as of 09/29/2005) - Determine the efficacy and safety of non-myeloablative chemotherapy ...

Phase

Collection of Blood Bone Marrow Tumor or Tissue Samples From Patients With Cancer to Study Drug Resistance

Background Ongoing research in the Experimental and Molecular Therapeutics Sections, NCI, requires the availability of blood, serum, tumor, hair follicle and tissue samples from patients with cancer. Resistance is the underlying cause of treatment failure, and may present as acquired or intrinsic drug resistance. Patients with cancer frequently present with ...

Phase N/A

Collection of Blood and Urine From Patients Undergoing Radiation Therapy

BACKGROUND Evolving research initiatives in the Radiation Oncology Branch (ROB) NCI, depend upon the availability of blood and urine samples from patients receiving radiotherapy. Examples of planned studies include an exploration of the effects of radiotherapy on peripheral leukocyte phenotype, peripheral blood protein and metabolism changes as well as measurements ...

Phase N/A

Collection of Blood From Patients With Cancer

Background Correlative studies performed on biospecimens of human subjects can be used to investigate the biology of solid tumors, inform the development of new strategies for treating those cancers, and evaluate these new therapeutic approaches. Specific areas of interest include, but are not limited to: the underlying mechanisms of tumor-specific ...

Phase N/A

Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation

OBJECTIVES: - Compare the incidence and severity of oral mucositis in children undergoing NASA-developed light-emitting diode (LED) therapy during a pre-transplantation myeloablative conditioning regimen (chemotherapy with or without radiotherapy) and continuing through the post-bone marrow transplantation (BMT) phase versus LED therapy during the post-BMT phase only. OUTLINE: This is a ...

Phase

Screening Individuals and Families at High Risk for Hematologic Cancers

OBJECTIVES: - Ascertain individuals at high risk for hematologic malignancy because of personal or family medical history. - Evaluate and define the clinical spectrum and natural history of disease in syndromes predisposing these individuals and families to hematologic cancer. - Evaluate the potential precursor states of malignancy in families at ...

Phase N/A

Imatinib Mesylate With or Without Interferon Alfa or Cytarabine Compared With Interferon Alfa Followed by Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

OBJECTIVES: - Compare the hematologic, cytogenetic, and molecular response rates in patients with newly diagnosed chronic phase chronic myelogenous leukemia treated with imatinib mesylate alone or with interferon alfa or low-dose cytarabine vs interferon alfa standard therapy. - Compare the group-dependent, progression-free and overall survival and time to progression in ...

Phase