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Fever Clinical Trials

A listing of Fever medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (30) clinical trials

Cohort Event Monitoring Study of Pyramax

This is a non-comparative Cohort Event Monitoring study. The study will assess the safety of Pyramax in terms of the evaluation and identification of the hepatic safety events in a sub group of patients enrolled with liver function tests (LFT)s >2x upper limit of normal (ULN) from blood taken immediately ...

Phase

Effect of Albumin Administration on Vasopressor Duration in Resolving Septic Shock

The role of albumin in sepsis has been controversial for decades. Although hypoalbuminemia has been associated with worse outcomes in sepsis, definitive evidence does not exist that replacing albumin in these patients improves outcomes. However, subgroup analyses from large clinical trials indicate that albumin may reduce mortality in septic shock, ...

Phase

Immunogenicity of Co-administered Yellow Fever and Measles Mumps and Rubella (MMR) Vaccines

The World Health Organization (WHO) and the Pan American Health Organization recommend that yellow fever and measles, mumps and rubella (MMR) vaccines be administered on the same day or at least 4 weeks apart to prevent interference between live vaccines. In 2011 a Brazilian study demonstrated lower seroconversion against yellow ...

Phase

Dex on Microcirculation in SS A Double-blinded Study

Dexmedetomidine is a highly selective 2-adrenoreceptor agonist for sedation of adult critically ill patients which exhibits sedative and analgesic effects. Recent studies suggest that dexmedetomidine to restore adrenergic vasoconstrictor responsiveness in septic shock, and prevents alterations of pain rat model intestinal microcirculation Induced by surgical stresseven it can reduce the ...

Phase

Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis

The secondary objectives of this study are: Determine whether the current recommended doses of caspofungin achieve the Pharmacokinetic/Pharmacodynamic (PK/PD) target for this molecule. Determine whether the current recommended doses of micafungin achieve the PK / PD target for this molecule Describe the peritoneal concentrations of echinocandins in secondary peritonitis complicated ...

Phase

Scrub Typhus Antibiotic Resistance Trial

Study type: Randomized Control Treatment Trial Study population: Male and female patients with 15 years of age and acute scrub typhus Duration: 2 years Study Design: Prospective, open-label, randomized-controlled treatment trial in patients 15 years old admitted to hospital with acute scrub typhus. Randomization into 3 oral treatment arms (each ...

Phase

Ketotifen as a Treatment for Vascular Leakage During Dengue Fever

Approximately 230 million individuals are infected each year by dengue virus (DENV) a Flavivirus spread by mosquito vectors that causes substantial worldwide morbidity and mortality. Infection by DENV results in dengue fever (DF), which is usually a self-limiting illness. However, many individuals can experience much more severe forms of disease, ...

Phase

Evaluating in Cirrhotics With Refractory Vasoplegia the Effect of Methylene Blue

Mortality rates associated septic shock remains unacceptably high, around 20-50%, with refractory hypotension in half of these patients. Widespread vasodilatation involves the activation of the soluble intracellular enzyme guanylate cyclase (GC) by nitric oxide (NO), resulting in the production of cyclic guanosine monophosphate (cGMP). Initially discovered as an endothelium-derived relaxing ...

Phase

Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China

Investigational drugUlinastain for Injection Study title A Prospective, Multi-Centre, Double-Blind, Randomized, Placebo-Controlled, Trial of Ulinastatin Treatment in Adult Patients with Sepsis and Septic Shock in China Principal InvestigatorProfessor Bin Du, Medical Intensive Care Unit, Peking Union Medical College Hospital; Professor Xiangyou Yu, Critical Care Medicine, First Affiliated Hospital, Xinjiang Medical ...

Phase

Effects of Levosimendan and Milrinone on Left and Right Ventricular Function in Septic Cardiomyopathy

This is a prospective randomized study where 30 patients with septic shock and myocardial dysfunction in echocardiogram, during the care in ICU, will be included. Patients with a history of previous heart disease will be excluded from the study. Each patient will be randomized and blinded to receive either milrinone ...

Phase