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Fever Clinical Trials

A listing of Fever medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (30) clinical trials

Ketamine Versus Fentanyl for Induction of Anesthesia in Septic Shock

Induction of anesthesia in hemodynamically compromised patients is a challenge for every anesthetist. Most of the intravenous induction agents have a negative effect on arterial blood pressure and cardiac output. Theoretically, the "ideal" emergency induction intravenous anesthetic should achieve rapid hypnosis and maintain the hemodynamic stability. Ketamine has been reported ...


Community-led Responses for Elimination: Controlled Trial of Reactive Case Detection Versus Reactive Drug Administration

The study is a cluster randomized controlled trial designed to evaluate the impact of RFDA intervention against current standard of care for the impact on seropositivity in children under five years, passive surveillance for confirmed malaria case incidence, and elimination of transmission from hotspots. It will be conducted among a ...


Cohort Event Monitoring Study of Pyramax

This is a non-comparative Cohort Event Monitoring study. The study will assess the safety of Pyramax in terms of the evaluation and identification of the hepatic safety events in a sub group of patients enrolled with liver function tests (LFT)s >2x upper limit of normal (ULN) from blood taken immediately ...


Propafenone Versus Amiodarone in Septic Shock

Primary aim is to verify the conclusions of the retrospective study, i.e. efficacy and safety of propafenone, in a prospective blinded randomized trial performed in two large intensive care units. Secondary aims are to monitor the electromechanics of left atrium in patients with SV arrhythmias in septic shock.


Effect of Albumin Administration on Vasopressor Duration in Resolving Septic Shock

The role of albumin in sepsis has been controversial for decades. Although hypoalbuminemia has been associated with worse outcomes in sepsis, definitive evidence does not exist that replacing albumin in these patients improves outcomes. However, subgroup analyses from large clinical trials indicate that albumin may reduce mortality in septic shock, ...


Immunogenicity of Co-administered Yellow Fever and Measles Mumps and Rubella (MMR) Vaccines

The World Health Organization (WHO) and the Pan American Health Organization recommend that yellow fever and measles, mumps and rubella (MMR) vaccines be administered on the same day or at least 4 weeks apart to prevent interference between live vaccines. In 2011 a Brazilian study demonstrated lower seroconversion against yellow ...


Dex on Microcirculation in SS A Double-blinded Study

Dexmedetomidine is a highly selective 2-adrenoreceptor agonist for sedation of adult critically ill patients which exhibits sedative and analgesic effects. Recent studies suggest that dexmedetomidine to restore adrenergic vasoconstrictor responsiveness in septic shock, and prevents alterations of pain rat model intestinal microcirculation Induced by surgical stresseven it can reduce the ...


Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis

The secondary objectives of this study are: Determine whether the current recommended doses of caspofungin achieve the Pharmacokinetic/Pharmacodynamic (PK/PD) target for this molecule. Determine whether the current recommended doses of micafungin achieve the PK / PD target for this molecule Describe the peritoneal concentrations of echinocandins in secondary peritonitis complicated ...


Scrub Typhus Antibiotic Resistance Trial

Study type: Randomized Control Treatment Trial Study population: Male and female patients with 15 years of age and acute scrub typhus Duration: 2 years Study Design: Prospective, open-label, randomized-controlled treatment trial in patients 15 years old admitted to hospital with acute scrub typhus. Randomization into 3 oral treatment arms (each ...


Ketotifen as a Treatment for Vascular Leakage During Dengue Fever

Approximately 230 million individuals are infected each year by dengue virus (DENV) a Flavivirus spread by mosquito vectors that causes substantial worldwide morbidity and mortality. Infection by DENV results in dengue fever (DF), which is usually a self-limiting illness. However, many individuals can experience much more severe forms of disease, ...