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Diabetic Kidney Disease Clinical Trials

A listing of Diabetic Kidney Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (37) clinical trials

A research study is evaluating an investigational medication for kidney disease due to diabetes (diabetic nephropathy). This research study may be an option if you: • Are 18 years old or older • Are male or a postmenopausal woman, or a female without childbearing potential • Have impaired kidney function ...

Phase N/A

Effects of Dapagliflozin in Non-diabetic Patients With Proteinuria

Despite optimal treatment with renin-angiotensin-aldosterone-system (RAAS) inhibitors, many patients with non-diabetic kidney disease show progressive kidney function loss, which is associated with high residual proteinuria. Novel treatment strategies are therefore required to further decrease proteinuria and to slow kidney function decline. Dapagliflozin is a sodium-glucose transport (SGLT2) inhibitor and inhibits ...

Phase

Low Energy Shockwave Therapy (LE-SWT): A Novel Treatment for Chronic Kidney Disease

1.0 Background 1.1 Definitions of chronic kidney disease The Kidney Disease Outcomes Quality Initiative (K/DOQI) of the National Kidney Foundation (NKF) defines chronic kidney disease as either kidney damage or a decreased glomerular filtration rate (GFR) of less than 60 mL/min/1.73m2 for 3 or more months. Whatever the underlying etiology, ...

Phase N/A

Spironolactone & RAAS: Effect on Urinary Proteinuria & Mean Epidermal Growth Factor Receptor

Determine the safety and efficacy of combination drug therapy in under-represented populations and to evaluate the efficacy of current clinical practices that involve the treatment of diabetic nephropathy with a combination of Angiotensin-Converting-Enzyme (ACE) inhibitors and mineralocorticoid receptor antagonists(MRA). The trial that will examine the safety and efficacy of combination ...

Phase

Efficacy and Safety of Canagliflozin (TA-7284) in Patients With Diabetic Nephropathy

The purpose of this study is to evaluate the efficacy and safety of Canagliflozin (TA-7284) in Japanese patients with Diabetic Nephropathy, compared with placebo

Phase

NEPHSTROM for Diabetic Kidney Disease

The study will investigate, primarily, the safety, feasibility and tolerability and, secondarily, the preliminary efficacy of an allogeneic bone marrow-derived Mesenchymal Stromal Cell (MSC) therapy (ORBCEL-M) in study subjects with type 2 diabetes (T2D) and progressive diabetic kidney disease (DKD).

Phase

IvaBradinE to Treat MicroalbumiNuria in Patients With Type 2 Diabetes and Coronary Heart Disease

This is a multi-center, randomized, open-label, investigator-initiated study with a parallel design. Patients with type 2 diabetes and coronary heart disease who are microalbuminuric [urinary albumin excretion (UAE): 30-500 mg/day], will be randomized after informed consent, in a 1:1 ratio to the following treatment groups: Group : Ivabradine 5mg twice ...

Phase

Effect of the Teleconsultation of Renal Nutrition on Renal Function and Glycemic Control in Patients With DKD

Chronic kidney disease (CKD) is the result of various chronic-degenerative diseases, including diabetes mellitus. In Mexico, it is considered a catastrophic disease due to the increasing number of cases, high investment costs and human resources, limited infrastructure, late detection of the disease, and high rates of morbidity and mortality in ...

Phase N/A

Effect of Oral Supplementation With Curcumin in Patients With Proteinuric Diabetic Kidney Disease

Diabetic Kidney Disease (DKD) represents the fist cause of end-stage kidney disease in Mexico and the world, and it is characterized by the presence of hyperfiltration, glomerular hypertrophy, tubular albuminuria and mesangial matrix expansion, mainly by the oxidative stress and the pro-inflammatory state. Current treatments are limited on controlling proteinuria ...

Phase

Exercise Study Testing Enhanced Energetics of Muscle Mitochondria in CKD

Sarcopenia is a common complication of chronic kidney disease. Sarcopenia is defined by decreased muscle mass or function and is central to the frailty phenotype that is associated disability, hospitalization, and death. Sarcopenia is a common and devastating complication of chronic kidney disease (CKD). The investigators and others have demonstrated ...

Phase