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Constipation Clinical Trials

A listing of Constipation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (18) clinical trials

Assessment of Responsiveness to Treatment by Experience Sampling Method

The primary objective of this study is to assess the internal and external responsiveness of the ESM-PROM in examining changes in symptom scores between baseline and post-treatment. Secondary objectives are to identify differences in characteristics between responders and non-responders to linaclotide and to assess for side effects of linaclotide treatment, ...

Phase N/A

Naloxegol Health Outcomes PASS

The overall research goal for this study is to provide additional data to characterize the safety of naloxegol in the indicated population and within at-risk vulnerable populations identified in the naloxegol risk management plan (RMP) by describing type and frequency of identified and potential risks (including bowel perforation, acute MI, ...

Phase N/A

Naloxegol Drug Utilization PASS

The overall research questions for this study are: 1) What are the demographic, clinical, and treatment characteristics (including dose) at baseline of patients prescribed naloxegol in real-world practice (including the use of naloxegol in non-indicated populations)? and 2) What are the treatment patterns of naloxegol utilization during follow-up? Primary objectives: ...

Phase N/A

Fecal Calprotectin Collection Protocol

Stools will be collected and tested, at a later date, in a clinical performance study with an investigational Calprotectin assay. This study will be coordinated by the Sponsor.

Phase N/A

The Comorbidity of Benign Hypermobility Joint Syndrome and Functional Constipation in Children

Clinical question: Is there among patients with functional constipation increased percentage of children with Benign Hypermobility Joint Syndrome, compared with a population of healthy children? In discussion we would like to determine whether the excessive laxity of connective tissue can promote the development of functional constipation in children. Description of ...

Phase N/A

Using 16S rRNA Gene Sequencing Analysis Intestinal Microbiota in Constipation Patients

Constipation is a frequent, chronic gastroenterological problem that has many varied symptoms and thus has several clinical definitions. According to the Rome III criteria for chronic constipation, almost 16% of all adults are affected by chronic constipation worldwide, and it is more prevalent and symptomatic in women and elderly people. ...

Phase N/A

Vitamine d Dosage and Constipation

Constipation is a disease that involves poor intestinal functioning. The reduced intestinal motility slows down intestinal function. Up to make lower the dosage of vitamin D. Vitamin D helps many cellular activities and enhances the action of tissue,Its Your dosage allows you to evaluate the efficacy of intestinal function and ...

Phase N/A

Biomarkers for Intestinal Permeability in Patients With Constipation

In order to determine the differences in permeability in IBS-C in comparison with healthy volunteers, the following will be determined: differences in in vivo small intestinal and colonic permeability, differences in small intestinal and colonic mucosal barrier function, differences in effects of fecal supernatants on barrier function of T84 monolayers, ...

Phase N/A

Factors Affecting Dissatisfaction to Treatments in Patients With Chronic Constipation and IBS With Constipation

Introduction: Chronic constipation (CC) and Irritable Bowel Syndrome with Constipation (IBS-C) are two overlapping conditions in which the patients are dissatisfied of their bowel habit. In a non negligible proportion of patients, the dissatisfaction persists after a first line treatment with effective laxatives such as macrogol and bisacodyl. Prucalopride and ...

Phase N/A

Cognitive and Psychiatric Effects of Linaclotide on Patients With Constipation

Irritable bowel syndrome (IBS) is a chronic, disabling functional gastrointestinal disorder that is characterized by abdominal pain or discomfort and a disturbance in bowel habit. It has long been recognized that psychological factors can be important in IBS, and that bi-directional signaling between the gut and the brain is likely ...

Phase N/A