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Diabetic Foot Ulcers Clinical Trials

A listing of Diabetic Foot Ulcers medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (92) clinical trials

Hyperbaric Oxygen Therapy and Angiogenesis in Diabetic Patients With Foot Ulcers

Diabetic foot ulcers are a major cause of morbidity and mortality, accounting for approximately two-thirds of all non-traumatic amputations performed in the United States. The cost of foot ulcers in diabetic patients averages almost $28,000 for the two years after diagnosis of the ulcer. Hyperbaric oxygen (HBO) serves as primary ...

Phase N/A

Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study

The criteria for considering a wound biopsy in a given patient are a chronic wound (venous leg ulcer, diabetic foot ulcer, decubitus ulcer) that has been present for over two (2) months and has failed to progress towards healing (less than 20% decrease in size over 2-week period of time). ...

Phase N/A

Trial of Herb Yuyang Ointment to Diabetic Foot Ulcer

1. Developing a Document Retrieval strategy for clinical trials of Chinese medicine treatment of diabetic foot ulcer according to the research program(finished) 2. Selecting and Evaluating the above trials,developing a methodological quality evaluation criteria(finished) 3. extract information, verification, meta-analysis, sensitivity analysis and sub-group analysis(finished) 4. comprehensive evaluating the pros and ...


Monochromatic Phototherapy on Diabetic Foot Ulcers

Description of Biolight® Therapy and device The therapy works by applying, for each indication, a specific combination of pulsating monochromatic light to specific areas of the body. The therapy is non-invasive, non-thermal, and based on the effects of pulsed monochromatic light in the visible or near-visible spectrum. The Biolight® Therapy ...


Wound Healing Endpoint and Recurrence

This prospective pilot study is to enroll patients with clinically-defined infected wounds. Patients enrolled in the study will be followed for 16 weeks for wound closure (Phase A), and will then begin Phase B. Wounds will be subjected to Standard of Care (SoC) followed by all Comprehensive Wound Center (CWC) ...

Phase N/A

Topical Oxygen Therapy for Diabetic Wounds

There are a total of 5 study visits including the initial baseline visit were they will be randomized into one of the 2 groups (comparison or treatment). At the baseline visit the following will be collected; history of the patient, physical examination of the patient including:, digital imaging of the ...

Phase N/A

Negative Pressure Wound Therapy as a Drug Delivery System

The investigators will enroll 150 patients from two centers: The University of Texas Southwestern University Hospital and Parkland Hospital. The investigators will screen and enroll patients with wounds in the inpatient setting. Patients will be randomized to receive traditional NPWT or NPWT with continuous irrigation while they are hospitalized. The ...

Phase N/A

Dipeptidyl Peptidase 4 Inhibition Facilitate Healing of Diabetic Ulcers

Groups Diabetic ulcers, saxagliptin + Regular treatment. Diabetic ulcers, placebo + Regular treatment. Time Point: Initial treatment; Post-treatment ( 1w ); Post-treatment ( 2w ); Post-treatment ( 4w ); Completely healed.


Pressure-Sensing Insoles in the Neuropathic Ulcer Treatment Pathway

Pressure offloading is the lynchpin of neuropathic ulcer care. Multiple methods of statically reducing pressure have been employed, with various degrees of success, in the ulcer care continuum. Traditional offloading interventions redistribute the load on the plantar surface, and include: non-removable devices (total contact casts, removable walkers rendered non-removable, and ...

Phase N/A

A Study of Granexin Gel to Treat Diabetic Foot Ulcer

DFU patients will undergo a one week screening period and those with changes in ulcer size of less than 30% will be eligible for randomization providing all other criteria are met. Participants enrolled in the study will receive treatment based on randomization into 1 of 2 treatment arms for up ...