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Kidney Disease Clinical Trials

A listing of Kidney Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (46) clinical trials

Safety of Low Dose IV Contrast CT Scanning in Chronic Kidney Disease

The use of radio contrast medium enhances the image quality of CT scans. However, contrast CT is avoided in patients with CKD for fear of contrast-induced nephropathy. The current standard of care for these patients is CT without contrast. Taking advantage of fast scanning capabilities of modern CT scanners (64-Multi-Detector ...

Phase

Quality of Life in Patients With Double Loop Ureteral Stent (JJ Silicone Hydrogel Study)

- The double loop stents are used for both prevention and treatment of ureteral obstruction: They permit the interim internal bypass drainage of urine when obstruction in the ureter especially in cases of lithiasis or after surgical intervention on the upper urinary tract. - There are many indications for double ...

Phase

Belatacept in Kidney Transplantation of Moderately Sensitized Patients

This exploratory single-center, open-label safety and efficacy study will enroll 20 adult kidney transplants candidates, moderately sensitized against their deceased donor and at-risk for delayed graft function (DGF), to receive Belatacept (days 0,5, weeks 2,4,8 and 12 (10 mg/kg), and every 4 weeks thereafter (5 mg/kg)), plasma exchange (once before ...

Phase

Assessing DSA Formation Diabetes Viral Infections Structural Kidney Changes With an Everolimus-based Regimen (ADVISE)

Patients enrolled in the core study CRAD001A2433 in Australia will be eligible for recruitment into CRAD001AAU13. These patients will undergo additional tests (including 4 kidney allograft biopsies) as part of the substudy that will be conducted during core study CRAD001A2433 visits. At Day 0 (day of transplant /TX), Month 2, ...

Phase

Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporineversus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A

Cytomegalovirus (CMV) infection is the most frequent opportunistic viral infection after kidney transplantation. Therefore most of the patients receive an universal prophylaxis. On the contrary to CMV naïve patients, seropositive recipients (R+) have already mounted a specific immunologic response directed against the virus, which is not completely abrogated by immunosuppressive ...

Phase

Post Marketing Surveillance for ICE-SENSE 3 a Cryotherapy Treatment of Renal Cell Carcinoma

A post marketing data collection of a cryosurgical system [ICESENSE™3 of IceCure Medical], for the treatment of renal cell carcinoma (RCC).

Phase

A Study of Ferric Citrate to Improve Inflammation and Lipid Levels

In patients with end stage renal disease (ESRD) receiving dialysis, the risk of cardiovascular death has been estimated to be 10-100 times higher than the general population without renal disease. This is due in part to high levels of inflammation and vascular calcification (large deposits of calcium in arteries) found ...

Phase

A Randomized Pharmacodynamic Comparison of Low Dose Ticagrelor to Clopidogrel in Patients With Prior Myocardial Infarction

Taken together the results from CHARISMA and PEGASUS-TIMI54, it appears that physicians may consider extending beyond 1 year or reinitiating treatment with clopidogrel 75 mg od or ticagrelor 60mg bid in patients with a prior MI and features of high ischemic and low bleeding risk. Comparative clinical or pharmacodynamic studies, ...

Phase

Renoprotective Effects of Dapagliflozin in Type 2 Diabetes

Study design A phase 4, monocenter, randomized, double-blind, comparator-controlled, parallel-group, mechanistic intervention trial to assess the effect of 12-week treatment with the sodium-glucose linked transporters (SGLT)-2 inhibitor dapagliflozin versus the sulfonylurea (SU) derivative gliclazide on renal physiology and biomarkers in metformin-treated patients with type 2 diabetes mellitus (T2DM) Recruitment Subjects ...

Phase

Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery

Neuromuscular blockade (NMB) is frequently utilized in laparoscopic procedures to improve surgical conditions by relaxing the abdominal muscles and thus facilitating insufflation with carbon dioxide to optimize surgical view. Increased airway pressures can lead to an increase in alveolar and perivascular edema, a decline in dynamic lung compliance and hypoxemia. ...

Phase