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Effects of Chemotherapy Clinical Trials

A listing of Effects of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (15) clinical trials

Strategy of Surgical Resection With Adjuvant Therapy for IIIA NSCLC and N2 Disease Only in Subaortic or Paraaortic Level

Stage IIIA non-small cell lung cancer (NSCLC) is a very heterogeneous disease and current treatment guidelines recommend concurrent chemoradiation therapy or combined neoadjuvant chemotherapy, surgical resection, and sequential adjuvant therapy. When incidental N2 disease is found despite thorough preoperative staging, adjuvant platinum-based chemotherapy with or without adjuvant radiotherapy is recommended. ...

Phase N/A

Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery

The broad goal of this research project is to develop a core set of biomarkers for chemotherapy-related cognitive impairment (or chemobrain). Clinical studies have documented mild cognitive impairment in chemotherapy patients most frequently within the domains of attention and memory, though impairments have been observed across a broad range of ...

Phase N/A

Intra-peritoneal Chemotherapy in Ovarian Cancer

Ovarian cancer is the third most common gynecological malignancy worldwide. Because of late, aspecific symptoms, the disease is usually diagnosed at an advanced stage. Most patients experience recurrence and die as a result of the disease within 5 years. Treatment is a combination of surgical debulking and systemic administered chemotherapy. ...

Phase N/A

Ovarian Reserve After Cancer: Longitudinal Effects

A total of 7 study visits will be completed at 3 month intervals including 1 visit prior to treatment, and at least 2 visits after completion of treatment. Duration of study participation is 18-30 months, depending on length of treatment. Review and Documentation of Cancer Therapy will be abstracted from ...

Phase N/A

Assessing Fertility Potential in Female Cancer Survivors

Up to 400 females will participate in this study in one of three cohorts: 150 females ages 11-35, with history of exposure to alkylating agent chemotherapy and/or radiation therapy 150 Unexposed peers, ages 11-35, never exposed to chemotherapy or radiation therapy 100 Unexposed females, ages 40-50 never exposed to chemotherapy ...

Phase N/A

Cologne Cohort of Neutropenic Patients (CoCoNut)

This prospective cohort was established with the aim of a comprehensive data collection of all patients developing neutropenia after receiving chemotherapy for any kind of malignant disease, treated in the University Hospital of Cologne.

Phase N/A

Short Term Genetic Effects of Chemotherapy on Male Germ Cells

While medical advances in the area of cancer treatment have successfully improved the overall detection and treatment of many cancers affecting men and women alike, these very treatment modalities can adversely affect their reproductive capacity. Certain types of chemotherapy, such as alkylating agents, are notorious for placing patients at high ...

Phase N/A

Peripheral Physiological Measures as Determinants of Pain Risk

Using MEM for peripheral sensory and motor axons we want to identify a set of excitability measures that: Correlate with parameters of clinical pain and of pain processing in existing pain patients (cross sectional study), with the aim to obtain an objective Pain Biomarker. Predict development of neuropathic pain in ...

Phase N/A

Effects of Modern Chemotherapy Regimens on Spermatogenesis and Steroidogenesis in Adolescent and Young Adult (AYA) Survivors of Osteosarcoma

PRIMARY OBJECTIVES: I. Determine whether infertility and/or biomarkers of spermatogenesis and steroidogenesis differ in male osteosarcoma survivors treated with cisplatin with or without ifosfamide compared to male controls without a history of cancer. II. Evaluate whether cisplatin with or without ifosfamide for the treatment of osteosarcoma alters sperm deoxyribonucleic acid ...

Phase N/A

TACkLE Study - Tackling Adverse Chemotherapy-associated Late Effects

Design: The investigators will perform a multicenter case-cohort study. Patients treated for TC who developed cardiac disease ((either myocardial infarction, proven coronary artery disease (grade 2) or congestive heart failure (grade 2)) will be invited by their (former) treating oncologist to participate in this study (cases). Furthermore, in each hospital ...

Phase N/A