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Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (49) clinical trials

Effectiveness of Bupropion for Treating Nicotine Dependence in Young People

Cigarette smoking and other forms of tobacco exposure are one of the leading preventable causes of morbidity and mortality in the United States. Most smokers begin smoking during adolescence, and though they seem motivated to quit smoking, they frequently fail. Although behavioral treatments are available, they have not been very ...

Phase

Brief Intervention to Reduce STDs in ER Drug Users - 1

Project SAFE is a multidisciplinary effort to test whether brief motivational interviewing in an emergency department setting may encourage change in sex behaviors and thus prevent gonorrhea, chlamydia, and HIV among male and female patients aged 18-44 years who use heroin and/or crack/cocaine and are not in treatment. We will ...

Phase

CHERL Connecting Primary Care Patients With Community Resources to Facilitate Behavior Change

What is this about? Prescription for Health (P4H) is a national initiative funded by the Robert Wood Johnson Foundation. Nine projects have been funded nationally in this second round to advance the goals of improving health behavior identification and delivery in primary care practice. Each project is conducted through a ...

Phase

Comparative Effectiveness of Two Tobacco Cessation Interventions for Employees of Partners HealthCare Inc.

Specific Aim: To conduct a randomized controlled trial among permanent employees of Partners HealthCare, Inc., and their adult dependents, who are current tobacco smokers. The trial will compare two interventions designed to help smokers stop using tobacco: (1) External Coaching Program (Standard Care) and (2) Internal Coaching Program, a chronic ...

Phase N/A

Babies Living Safe and Smokefree

The purpose of this randomized controlled trial is to develop and test the efficacy of a multilevel, multimodal intervention designed to reduce children's exposure to secondhand tobacco smoke (primary outcome) and promote smoking cessation in mothers (secondary outcome). Low-income mothers who smoke and their children will be enrolled from the ...

Phase N/A

Stage Ib Trial of mSMART for Smoking Cessation Medication Adherence

Poor medication adherence (a) results in poorer treatment outcome and (b) accounts for $100 to $290 billion in U.S. healthcare costs annually. Therefore, interventions that target medication adherence are increasingly crucial for patient care and cost-effectiveness. Mobile technologies such as smartphones are increasingly ubiquitous and affordable in the U.S., and ...

Phase N/A

A Clinical Decision Support Tool for Electronic Health Records

For behavioral health clinicians who are interested in getting tailored treatment and level of care recommendations, "BH-CDS" is a desktop/tablet web-based application that provides clinicians with data and a rationale for better decision-making to improve patient care. Few Clinical Decision Support (CDS) systems are available for Behavioral Health, and unlike ...

Phase

Arise: An Online Relapse Prevention Tool for Adolescent Substance Abusers

Purpose: In Phase I of this SBIR project, 3C Institute (3C) developed a working prototype of For Life (henceforth Arise), an innovative computer-based coping skills educational program for adolescent substance abuse treatment completers. For Phase I, 3C developed and tested two customizable intelligent educational modules to teach coping skills in ...

Phase

Structured Discontinuation vs Continued Therapy in Suboptimal and Optimal Responders to High-dose Long-term Opioids for Chronic Pain

The purpose of this study is to evaluate the effect on pain intensity (PI) of structured discontinuation of long-term opioid analgesic therapy compared to continuation of opioid therapy in Suboptimal and Optimal Responders to high-dose, long-term opioid analgesic therapy for chronic low back pain (CLBP).

Phase

Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers

Objective The primary objective of this study is to determine the pharmacokinetic profile of a single dose of Nicotine Sublingual Tablets, 4 mg (Test Product) versus Nicorette Lozenge 4 mg in healthy adult smokers when administered under fasted conditions. Study Design This is an open-label, pseudorandomized, two-way crossover comparison of ...

Phase