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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (2132) clinical trials

Researchers at the University of Kentucky Gill Heart Institute are inviting you to learn more about a clinical study for blood pressure that is not adequately controlled with medications. Researchers are investigating a device to lower blood pressure that is beyond lifestyle and medication changes. This clinical study involves approximately ...

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Researchers at the University of Kentucky Gill Heart & Vascular Institute are inviting you to participate in a clinical research study evaluating an investigational implantable device designed to send electrical signals to balance the cardiovascular system. To learn more, visit: www.HeartFailureStudy.com

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In patients with symptomatic New York Heart Association (NYHA) Class II/III/IV dilated cardiomyopathy (DCM) in which mutations in the gene encoding the lamin A/C protein (LMNA) have been implicated: Primary Objective: NYHA Class II/III patients only: Evaluate the effect of ARRY-371797 on functional capacity (as measured by the 6-minute walk ...

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This study is designed as a multi-center prospective observational study of diagnosed Heart Failure (HF) patients to test the hypothesis that additional Ejection Fraction (EF) recovery occurs between 90 and 180 days as Guideline Directed Medical Therapy (GDMT) is achieved.

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STeroids to REduce Systemic Inflammation After Neonatal Heart Surgery

Overview Congenital heart diseases (CHD) are the most common birth defects, occurring in nearly 1% of live births. Every year, an estimated 40,000 infants born in the U.S. suffer from CHD. Despite advances in surgical management, CHD requiring neonatal surgery is associated with poor outcomes; national registry data demonstrates post-operative ...

Phase

Heart and Muscle Metabolism in Barth Syndrome

Barth syndrome (BTHS) is an X-linked disorder characterized by abnormal cardiolipin metabolism, mitochondrial dysfunction, muscle wasting and heart failure. BTHS is a particularly significant disease as it is often fatal in childhood and there are no approved therapies for BTHS other than the standard treatment of heart failure. Therefore novel ...

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Combined Use of Multiple Biomarkers With Stress Testing to Detect Coronary Artery Disease

The COMBAT-CAD Study is an observational study with the aim to improve the diagnostic accuracy by a combination of stress testing with sensitive and specific biomarkers in detecting coronary artery disease or its progress. The main subjects are all patients with CAD or suspicion of CAD sent to the University ...

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PARTNER 3 Trial - Mitral Valve in Valve

A prospective, single-arm, multicenter clinical trial. This study will enroll patients with symptomatic heart disease due to a failing bioprosthetic mitral valve (stenosed, insufficient, or combined).

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Registry of Unexplained Cardiac Arrest

Arrhythmias caused by congenital or acquired abnormalities of cardiac K+ or Na+ channels are increasingly recognized as a cause of syncope and sudden death. Cardiac arrest in the absence of overt structural heart disease was previously considered idiopathic ventricular fibrillation (IVF). The list of causes of "unexplained" cardiac arrest (UCA) ...

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COlchicine for Left VEntricular Remodeling Treatment in Acute Myocardial Infarction

Inflammatory processes have been identified as key mediators of ischemia/ reperfusion injury in ST-segment elevation myocardial infarction. They add additional damage to the myocardium and are associated with clinical adverse events (heart failure and cardiovascular death) and poor myocardial recovery. All the different anti-inflammatory approaches to reduce reperfusion injury have ...

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