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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (86) clinical trials

A clinical trial seeking patients for a research study for the treatment of Myocardial Infarction, Autonomic nervous system disorders

Sudden cardiac death (SCD) is the most common single cause of death in the industrialized world. Patients after myocardial infarction (MI) are at increased risk of SCD. Current guidelines recommend prophylactic ICD-implantation in post-MI patients with reduced left ventricular ejection fraction (LVEF 35%). However, the majority of arrhythmic deaths after ...

Phase N/A

A clinical trial to evaluate treatments using Saxagliptin, Placebo to match saxagliptin, Sitagliptin, Placebo to match sitagliptin for patients with NIDDM, Heart failure

This is a 24 week, multicenter, randomized, double-blind, parallel group, placebo-controlled study to investigate the effects of saxagliptin and sitagliptin on cardiac dimensions and function in patients with type 2 diabetes (T2DM) mellitus and heart failure (HF).


Patients are needed to participate in a clinical research study evaluating Placebo, Omecamtiv Mecarbil

The purpose of this study is to determine if treatment with omecamtiv mecarbil/AMG 423 when added to standard of care is well tolerated and superior to placebo in reducing the risk of cardiovascular death or heart failure events in subjects with chronic HFrEF.


Patients are needed to participate in a clinical research study evaluating Hydroxychloroquine, Placebo for the treatment of Acute Coronary Syndrome, Inflammation, Antirheumatic Agents, Myocardial Infarction, Hydroxychloroquine, Cardiovascular Disease

Anti-rheumatic medications decrease cardiovascular mortality in rheumatoid arthritis patients, based mainly on their anti-inflammatory effect. No studies have addressed their effect on preventing recurrent cardiovascular events among non-rheumatic patients. In the pilot phase 200 myocardial infarction patients will be recruited during their index visit to the study hospitals. Patients will ...


A clinical trial seeking patients for a research study for the treatment of Chronic Stable Angina, Angina Pectoris, Angina Pectoris, Stable

This study is a multicenter, multi-country three-arm prospective and retrospective investigation in up to 400 subjects conducted at a maximum of 40 investigational centers. Arm 1 will include eligible prospective subjects. Arm 2 will include subjects who were previously enrolled and treated with the Reducer during the COSIRA (Coronary Sinus ...

Phase N/A

Patients are needed to participate in a clinical research study of Rivaroxaban, 7.5 mg, Placebo, Rivaroxaban, 10 mg

This is a randomized (the study medication is assigned by chance), double-blind (neither physician nor participant knows the identity of the assigned treatment), placebo (an inactive substance that is compared with a drug to test whether the drug has a real effect)-controlled, event-driven, multicenter study in patients who are hospitalized ...


A clinical research study for the treatment of Coronary Artery Disease, Coronary heart disease

This will be a prospective, observational study designed to include a convenience sample of all qualifying patients undergoing myocardial CTP. The study will enroll patients who have undergone a clinically indicated CCTA for suspicion of coronary artery disease and have a suspected coronary stenosis 50%-69% on that examination. CCTA is ...

Phase N/A

A clinical trial to evaluate treatments for patients with Diabetes Mellitus, Tachycardia, Cardiovascular Disease

In this study, subjects will be randomized to receive a subcutaneous implantable cardioverter defibrillator or Conventional Medical Therapy (CMT). Randomization will be stratified by enrolling site, in a 2:1 (S-ICD:CMT) scheme. Length of follow-up for each subject will be dependent on the date of entry into the study, since all ...

Phase N/A

A Phase 4 clinical study for patients with Atrial Fibrillation, Coronary Artery Disease, Acute Coronary Syndrome, Coronary heart disease

Patients with atrial fibrillation (AF) presenting an acute coronary syndrome (ACS) and undergoing PCI require a triple therapy with a combination of oral anticoagulation (OAC) and dual anti-platelet therapy. Current guidelines recommend a regimen consisting of aspirin, clopidogrel and an oral anticoagulant. Although effective in preventing recurrent ischemia, triple therapy ...


Patients are needed to participate in a clinical research study evaluating acetylsalicylic acid (ASA) therapy, Warfarin for the treatment of Heart failure

This is a post-market clinical study of HM II patient management practices to be conducted in the United States. Subjects will be randomized in a 1:1 fashion to the following research drug groups: Treatment Arm: Warfarin (INR target: 2.0-2.5, median: 2.25) + Placebo (1 pill/day) Control Arm: Warfarin (INR target: ...