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Heart Disease Clinical Trials

A listing of Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (124) clinical trials

Study Description: Multi-center, international, prospective, randomized, interventional, pre-market study. Patients will be seen at pre and post-procedure, discharge, 30 days, 6 months, 1 year, 18 months, and annually through 10 years. Randomly assigned (50% to either group) Treatment of Aortic Stenosis with either Transcatheter Aortic Valve Replacement (TAVR) device or ...

Phase

A 8 to 12 Week Randomized, Double-Blind Study to Compare the Fixed-Dose Combination of Telmisartan 80 + Amlodipine 10mg Versus Amlodipine 10mg Monotherapy as First Line Therapy in Type 2 Diebetes Patients with Hypertension (High Blood Pressure) Patient Inclusion Criteria: Men or Women 18 Years of Age or Older May ...

Phase

The purpose of the study is to evaluate whether a new antiplatelet therapy, Brilinta® (Ticagrelor) approved by the FDA, for the reduction of major cardiovascular events in patients with certain heart conditions, is effective in preventing the occurrence of heart attack, stroke and/or death due to cardiovascular events in patients ...

Phase

The purpose of this study is to investigate if rivaroxaban in combination with standard care (the other medications you are currently taking for your heart failure (HF) and coronary artery disease (CAD)) can reduce the risk of a heart attack, stroke or death in patients with Chronic Heart Failure and ...

Phase

WHAT IS THE SPIRE PROGRAM? The SPIRE program is a series of clinical studies that is investigating a study drug in people who have high cholesterol. This study drug is being evaluated to understand its effects on bad cholesterol (LDL-C) and cardiovascular events such as heart attack or stroke. The ...

Phase

"THE VERTIS CV STUDY" Type 2 Diabetes Mellitus and Established Vascular Disease Merck and Pfizer Announce Two Pivotal Phase 3 Studies for Ertugliflozin, an Investigational SGLT-2 Inhibitor, Met Primary Endpoints, Showing Significant A1C Reductions in Patients with Type 2 Diabetes http://www.mercknewsroom.com/news-release/corporate-news/merck-and-pfizer-announce-two-pivotal-phase-3-studies-ertugliflozin-inve

Phase

Clinical Trial on the Efficacy and Safety of Sirolimus-Eluting Stent (MiStent System)

- The study will enroll a total of 428 cases of primary in situ coronary artery disease patients (all patients enrolled with a maximum of two target lesions in different blood vessels and maximum of 2 stents per lesion. If more stents are needed for implantation, stents with the same ...

Phase

Effects of Nicorandil on Cardiac Infarct Size in Patients With ST-segment Elevation Acute Myocardial Infarction

Study objective : To investiage whether nicorandil treatment reduce infarct size measured by cardiac MRI at 6 months after primary PCI Allocation : 1. Nicorandil arm : Recieve nicorandil 4 mg i.v. before undergoing PCI, additionall 2mg i.c. just before 1st ballooning, additionall 2mg i.c. just before stenting, After successful ...

Phase

Absorb BVS vs. Drug Coated Balloon for Treatment Of ISR

This is randomized-controlled trial of Absorb® Bioresorbable Vascular Scaffold (BVS) vs. Sequent Please® drug coated balloon in an all-comers population with in-stent-restenosis (ISR). The patients will be randomized in a 1:1 fashion and the investigators intend to include 150 patients. All patients presenting with ISR and requiring percutaneous coronary intervention ...

Phase

Prevention of Hemorrhage After Implantation of Mechanical Circulatory Support

This time point was chosen because the bleeding events are maximal within the first 3 months after implantation. - Adult patients > 18 years who need a CF-LVAD due to advanced heart failure. - Functional To determine the potential indication of Wilfactin® in the field of CF-LVAD and avoid widespread ...

Phase