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Eczema (Atopic Dermatitis) Clinical Trials

A listing of Eczema (Atopic Dermatitis) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (20) clinical trials

Defining the Skin and Blood Biomarkers of Pediatric Atopic Dermatitis

Objectives To define the cellular and molecular biomarkers of atopic dermatitis in skin biopsies and blood samples from a pre-adolescent pediatric population and correlate it with disease severity. To measure the skin barrier in atopic dermatitis. To determine quality of life in atopic dermatitis through various questionnaires.

Phase N/A

Inflammatory Cells From Various Pathologies

Innovaderm, in collaboration with "The Immunoregulation laboratories of CRCHUM" and "McGill University division of dermatology", recently developed a novel 6-hour method to study IL-17A (Interleukin) and IL-22 from fresh biopsies of psoriatic patients. This reproducible experimental approach combines enzymatic digestion and mechanical dissociation for skin cell isolation. This is followed ...

Phase N/A

Anti-cytokine Signatures in Inflammatory Skin Disease

This pilot project intends to examine the utility of a systems medicine approach to identify regulatory networks and their perturbation in psoriasis and atopic dermatitis, and to obtain a comprehensive perspective on disease and disease control by integrating and modelling data across multiple cellular levels and time following specific blockade ...

Phase N/A

Systemic Therapies for Pediatric Atopic Dermatitis

Severe and/or refractory cases of atopic dermatitis (AD) can require systemic immunosuppressive therapy for disease control, yet there are few studies regarding the appropriate use of these drugs for pediatric AD and even less data comparing them. The current observational study will observe the effect of these therapies on children ...

Phase N/A

Linking Epidermal Barrier Function With Anti-Oxidant Defense Mechanisms in Atopic Dermatitis

Up to 40 healthy and 40 atopic dermatitis subjects meeting the inclusion criteria will be enrolled. Medical records will be reviewed pertaining to the subject's diagnosis of atopic dermatitis and specific therapeutic interventions. For atopic dermatitis subjects, AD severity will be assessed using Eczema Area and Severity Index (EASI). Study ...

Phase N/A

Disease Trajectories in Atopic Dermatitis and Psoriasis

Atopic dermatitis and psoriasis are the most common chronic inflammatory skin diseases in dermatology. Due to genetic predispositions, inflammatory changes of the skin occur. The specific immunological inflammatory mechanisms are partly understood for both diseases and targeted therapies are established in psoriasis therapy and are currently available for the first ...

Phase N/A

Registry for the Atopic Dermatitis Research Network

People with atopic dermatitis (AD), also known as eczema, experience hot, dry, scaly skin with severe itching. In addition, people with AD are prone to skin infections and inflammation. Little is known about the causes of AD or why people with AD are more prone to infections. The purpose of ...

Phase N/A

Identification of Epidermal Signatures in Patients With Atopic Dermatitis

Atopic dermatitis (AD) is a highly pruritic, chronic inflammatory skin disease that affects up to 25% of children and 10% of adults. Atopic skin disease is associated with significant morbidity as well as physical, psychological, and economical quality-of-life impairment. The economical impact of AD and the requirement for family support ...

Phase N/A

Natural History of Diseases Associated With Allergic Inflammation: Atopic Dermatitis and Genetic and Congenital Diseases Associated With Atopic Pathways

Background Allergic inflammation is central to the pathogenesis of allergic diseases, including atopic dermatitis, asthma, allergic rhinitis, and food allergy. These disorders are common, affecting up to 50 million Americans, and their pathophysiology remains poorly understood. Among allergic diseases, atopic dermatitis is common, with a prevalence of up to 20% ...

Phase N/A

Study of the Frequency and of the Regulatory Function of Positive T Lymphocytes Dual CD4CD8aa (DP8a) Specific to a Bacteria of the Intestinal Microbiota (Faecalibacterium Prausnitzii) in Atopic Dermatitis Asthma and Allergic Rhinitis

The primary endpoint will be the highlight of a quantitative reduction of double positive T cells (CD4 + / CD8 +) the specific F prausnitzii peripheral blood in patients with allergic asthma, allergic rhinitis and atopic dermatitis compared to samples from a control sample collection made available by the laboratory ...

Phase N/A