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Borderline Personality Disorder Clinical Trials

A listing of Borderline Personality Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (25) clinical trials

Methylation Status of BDNF Gene After Dialectical Behavior Therapy in BPD

Background: Borderline personality disorder (BPD) is a chronic and debilitating syndrome associated with considerable morbidity, mortality, and high rates of medical and psychiatric utilization services. The prevalence of BPD is around 1%-2% in general population. However, suicidality and self-injury are common, an estimated 69-80% of patients with BPD attempt suicide ...

Phase N/A

Connectivity and Social Cognition in Adolescent Girls With Borderline Personality Disorder a Pilot Study

The disruption of social cognition associated with borderline personality disorder (BPD), and more specifically categorization of facial emotions, remains largely under-studied, despite the high frequency of this pathology in the clinical population. The first results differ from the observations made in adults and this confirms the relevance of studying this ...

Phase N/A

Nalmefene in Alcohol Dependence and Borderline Personality Disorder

The objective is to study the effectiveness of Nalmefene in decreasing alcohol intake in subjects with alcohol use disorder and comorbid BPD.

Phase N/A

Training of Neural Responding in BPD

Patients with BPD show increased emotional reactivity, slow return to baseline, and severe emotion dysregulation symptoms. On the neural level, BPD patients hyper-activate the amygdala and hypo-activate the prefrontal cortex in response to emotional stimuli. The prefrontal cortex and the amygdala are crucial nodes of the brain's emotion regulation network ...

Phase N/A

Narrative Exposure Therapy in Women With Borderline Personality Disorder and Posttraumatic Stress Disorder

Narrative Exposure Therapy (NET) is an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity. Patients with Borderline Personality Disorder (BPD) often suffer from a comorbid Posttraumatic Stress Disorder (PTSD) caused by multiple traumatic events. Therapeutic aims are the reduction of PTSD-Symptoms ...

Phase N/A

Change in Mindfulness in Borderline Personality Disorder

Participants will be recruited from the Dialectical-Behavioral-Therapy (DBT) unit. DBT is a treatment approach that has been shown to be effective in the treatment of Borderline Personality Disorder. DBT integrates different psychotherapeutic interventions as well as Mindfulness Meditation exercises. Mindfulness is a meditation practice that can improve present moment awareness. ...

Phase N/A

Emotional and Cognitive Self-regulation an EEG Study

The main goal of the proposed project is to assess treatment-induced changes of electrophysiological and psychophysiological correlates of the capacity to regulate emotion, executive functions, and clinical measures in individuals with (complex) posttraumatic stress disorder, dissociative disorders, or borderline personality disorder in naturalistic inpatient and outpatient settings.

Phase N/A

Preschooler Emotion Regulation in the Context of Maternal Borderline Personality Disorder

Borderline personality disorder is a serious mental illness characterized by extreme emotions, chaotic interpersonal relationships, suicidal behaviors, and a poor sense of self. Offspring of mothers with Borderline Personality Disorder (BPD) are at an elevated risk for developing mental illness across the lifespan. Difficulty managing emotions are a hallmark feature ...

Phase N/A

Dialectical Behavior Therapy Rutgers University Research Program

This protocol establishes a research oriented psychological treatment clinic within the Graduate School of Applied and Professional Psychology (GSAPP), called the Dialectical Behavior Therapy Rutgers University Research Program (DBT-RU). The overall aim of the proposed research is to find ways to improve therapist training in existing treatments for complex and ...

Phase N/A

Low-Dose Risperidone Treatment for Subjects Suffering From Borderline Personality Disorder

Personality disorders are life-long maladaptive behavioral patterns. Borderline personality disorder (BPD) is the leading personality disorder encountered in clinical settings, often associated with tremendous distress. It is characterized by impulsivity, emotional lability, unstable interpersonal relationships, with particular sensitivity to abandonment. BPD patients are prone to self destructive behaviors and all ...

Phase N/A