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Liver Cancer Clinical Trials

A listing of Liver Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (799) clinical trials

ERAS Program Improves Recovery of HCC Patient Undergoing Hepatectomy

The first ERAS program was introduced by Kehlet in the 1990's. ERAS programs were initially implemented in colorectal surgery and have found their way into general clinical practice, including orthopedic, vascular, and thoracic surgery. In the field of liver surgery, cohort studies have been conducted and randomized trials have confirmed ...

Phase N/A

A Prospective Colorectal Liver Metastasis Database With an Integrated Quality Assurance Program

This prospective database has two main objectives; to evaluate the complication rates, 30-day and 90-day mortality from different surgical strategies for unresectable, borderline resectable or initially unresectable liver metastasis from colorectal cancer. to establish baseline quality parameters for different surgical strategies for unresectable, borderline and initially unresectable colorectal liver metastasis ...

Phase N/A

A Study of Combinations of D-CIK Immunotherapy And Anti-PD-1 In Refractory Solid Tumors

Heparinized peripheral blood was obtained from participants over a 2-week period. PBMCs were separated by Ficoll-Hypaque gradient centrifugation, suspended in X-VIVO 15 serum-free medium, and culture with 1000 U/ml rhIFN-for the first 24 h, followed by stimulation with 100 ng/ml OKT3 , 1000 U/ml rhIL-2 and 100 U/ml IL-1 to ...


Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma

Cholangiocarcinoma (CCA) is the second most common malignancy arising within the liver, and the association of this malignant condition with high morbidity and mortality is well recognized. It originates from the epithelium of bile ducts or ductules. Two types have been described: the peripheral type occurring in the parenchyma of ...


Microwave Ablation Versus Resection for Resectable Colorectal Liver Metastases

BACKGROUND Surgery Surgical resection of operable colorectal liver metastases is the current gold standard. With advancement in surgical techniques and technology the 3-year survival rate for this group of patients is now in the range of 60% [1] where the survival without resection is virtually non-existent. Palliative chemotherapy can prolong ...

Phase N/A

TheraSphere for Treatment of Unresectable Hepatocellular Carcinoma

This protocol provides TheraSphere treatment for patients with liver cancer who cannot be treated by surgery. Patients with hepatocellular carcinoma will be evaluated for eligibility for this treatment with the following: physical examination, medical history, blood tests requiring approximately 2 tablespoons of blood, EKG, CT or MR of chest to ...

Phase N/A

REgistry of Selective Internal Radiation Therapy in TaiwaN (RESIN)

All study objectives will be assessed in HCC patients or colorectal cancer patients with secondary metastases in the liver, respectively. Primary objective: To observe the safety of SIR-Spheres microspheres therapy (SIRT)by, Adverse events and serious adverse events (non-specific and radiation specific) Changes in liver function parameters To observe the efficacy ...

Phase N/A

Hepatic Arterial Infusion Chemotherapy(HAIC) for Hepatoma After Resection

The high incidence of HCC recurrence following liver resection is a serious issue. The recurrent rate is as high as 50-60% at 3 years and 70-100% at 5 years. So to reduce the recurrence rate of HCC, some interventions had been tried in clinic, including transarterial chemoembolization (TACE), immunotherapy, and ...


Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma

This is a two part, phase I, single centre dose escalation and dose expansion study to establish the safety, tolerability and pharmacokinetics of pembrolizumab in combination with different dose levels of fixed dose rate gemcitabine in patients with newly diagnosed metastatic or inoperable leiomyosarcoma and undifferentiated pleomorphic sarcoma (UPS), for ...


Phase II Multicenter Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression.

Non-randomized, open, single cohort, phase II, multicenter national clinical trial. 19 sites in Spain. Palbociclib will be administered orally at a dose of 125 mg once a day for 21 consecutive days followed by 7 rest days to comprise a complete cycle of 28 days. Treatment will continue until disease ...