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Malignant Melanoma Clinical Trials

A listing of Malignant Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (176) clinical trials

Safety Study of MGA271 in Refractory Cancer

An open-label, multi-dose, single-arm, multi-center, Phase 1, dose-escalation study will be conducted to define the toxicity profile, maximum tolerated dose (MTD), pharmacokinetics (PK), immunogenicity, and potential antitumor activity of MGA271 in patients with refractory cancer that expresses B7-H3. In the initial segments of the study, patients will be monitored for ...


Phase II Study of Nivolumab in Combination With Ipilimumab for Uveal Melanoma

Study Drug Administration: If you are found to be eligible to take part in this study, you will receive ipilimumab by vein over 90 minutes (+/- 15 minutes) each time. You will receive nivolumab by vein over 60 minutes (+/- 15 minutes) each time. You will receive ipilimumab and nivolumab ...


Romidepsin in Treating Patients With Lymphoma Chronic Lymphocytic Leukemia or Solid Tumors With Liver Dysfunction

PRIMARY OBJECTIVES: I. To establish the safety and tolerability of romidepsin given on days 1, 8, and 15 of a 28 day cycle to patients with varying degrees of liver dysfunction (mild, moderate and severe). II. To establish the maximum tolerated dose (MTD) and appropriate dosing recommendations for romidepsin in ...


Relevance of Imiquimod as Neo-adjuvant Treatment to Reduce Excision Size and the Risk of Intralesional Excision in Lentigo Malignant of the Face

The primary endpoint of the study is to demonstrate that neoadjuvant treatment of LM by imiquimod prior to surgery can reduce the frequency of intralesional excisions as from the first surgical procedure, with a healthy tissue margin of 5mm. Furthermore, the improvement in patient quality of life could also be ...


Phase II/III Clinical Study CSF470 Plus BCG Plus GM-CSF vs IFN Alpha 2b in Stage IIB IIC and III Melanoma Patients

Randomized, open, Phase II-III study, comparative between treatment with CSF-470 vaccine , allogeneic, irradiated with BCG and molgramostin (rHuGM-CSF) as adjuvants and interferon alfa 2b (IFN-alpha2b) treatment , in stages IIB, IIC o III (AJCC) post-surgery cutaneous melanoma patients. This study has been approved by ANMAT ( Administración Nacional de ...


Study of Lymphodepletion Plus Adoptive Cell Transfer With T-Cells Transduced With CXCR2 and NGFR Followed by High Dose Interleukin-2 in Patients With Metastatic Melanoma

Pretreatment Procedures: If you are found eligible to take part in this study, the following tests and procedures will be performed before you begin receiving any study drugs or treatments: Within 6 months before receiving cyclophosphamide and fludarabine: - You will have a lung function test. - You will have ...