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Thyroid Disease Clinical Trials

A listing of Thyroid Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (61) clinical trials

A clinical trial seeking patients for a research study for patients with Hypothyroidism switching from levothyroxine to desiccated thyroid extract

Phase N/A

PEN-221 in Somatostatin Receptor 2 Expressing Advanced Cancers Including Neuroendocrine and Small Cell Lung Cancers

Protocol PEN-221-001 will first enroll patients into a dose escalation phase, where a Bayesian logistic regression model, guided by the escalation with overdose control principle and overseen by a safety review committee, will be used to make dose recommendations and estimate the maximum tolerated dose (MTD). Once the MTD has ...

Phase

HuMax-AXL-ADC Safety Study in Patients With Solid Tumors

The trial consists of two parts; a dose escalation part (phase I, first in- human (FIH)) and an expansion part (phase IIa). The dose escalation part has two dose escalation arms: the first arm investigates a once every 3 weeks (1Q3W) dose schedule and the second one investigates a three ...

Phase

Motorized Spiral Colonoscopy Trial: A First Feasibility Trial

Colonoscopy has been widely accepted for the diagnosis and treatment of colon diseases. Properly performed, colonoscopy is generally safe, accurate, and well-tolerated. Diagnostic colonoscopy is the preferred method to evaluate the colon in most patients with large-bowel symptoms, iron deficiency anemia, abnormal results on radiographic studies of the colon, positive ...

Phase N/A

Single Dose Steroid Before Thyroidectomy for Benign Disease to Improve Postoperative Nausea Pain and Vocal Function

The purpose of this study is to evaluate the efficacy of 8 mg of dexamethasone administered prior surgery, to reduce pain, postoperative nausea and vomiting and to improve vocal function after thyroidectomy for benign disease.

Phase

Comparison of Iodine-124 (I-124) and Iodine-131 (I-131) Radiopharmacokinetics

Radiopharmacokinetics and Dosimetric Calculations A tracer dosage of either I-131 or I-124 is first administered to the patient, and the clearance is then followed for the specified period. In the classical approach, the blood is considered the critical organ which is irradiated either from the - particles emitted from activity ...

Phase N/A

Influence of Thyroid Hormones on the Woundhealing Process

Main goal of this clinical investigation is to investigate different cytokines in wound fluids of euthyroid vs. hypothyroid patients. As a primary endpoint we want to evaluate if different cytokine levels in euthyroid vs. hypothyroid patients exist and to what extent these cytokines differ. Our targeted cytokines are: IL6, IL10, ...

Phase N/A

Phase II Study of the Optimal Scheme of Administration of Pazopanib in Thyroid Carcinoma

Total or near-total thyroidectomy is the primary treatment for differentiated thyroid carcinoma. Postoperatively, DTC are treated with radioiodine (131I) and thyroid stimulating hormone (TSH) suppressive levothyroxine therapy. But 5% to 20% of patients with DTC develop distant metastases; some of them become refractory to 131I therapy. Targeted therapies have been ...

Phase

Evaluation of Patients With Thyroid Disorders

Patients with thyroid function abnormalities (hyperthyroidism, hypothyroidism) are studied and treated in this protocol. A limited number of patients with a personal history of signs, symptoms or laboratory studies consistent with thyroid dysfunction or a strong family history of thyroid abnormalities are also enrolled. Patients undergo routine history and physical ...

Phase N/A

Studies on Tumors of the Thyroid

The purpose of this study is to evaluate methods for preoperative diagnosis and therapy of thyroid cancer and to screen patients for participation in other protocols. Study subjects will include adults and children with thyroid nodules or cancer requiring diagnostic fine needle aspiration biopsy, surgery, radioiodine scanning or therapy for ...

Phase N/A