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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (271) clinical trials

Neuroplasticity in Auditory Aging_Project 2

The detrimental effects of aging on auditory temporal processing have been well documented in humans and animal models. At present, there are gaps in knowledge of the extent to which these auditory temporal processing deficits can be mitigated in older adults with or without hearing loss through auditory training and ...

Phase N/A

Inspiratory Muscle Strength Training to Improve Blood Pressure and Physiological Function

Over, the proposed research project has the long-term potential to influence clinical practice by establishing a novel lifestyle intervention for treating multiple domains of ageand hypertension-associated physiological dysfunction and thereby reducing the risk of clinical disease and disability.

Phase N/A

Prevention of Cardiovascular Stiffening With Aging and Hypertensive Heart Disease

The global objective of this project is to test novel strategies to prevent diastolic dysfunction associated with HFpEF; these include: a) identifying high risk individuals by using population derived imaging and blood biomarkers; and b) implementing novel exercise training strategies in these middle age individuals, when cardiac plasticity still exists, ...

Phase N/A

Multisensory Perceptual Training in the Elderly

The investigators will examine the training effects in the elderly by comparing the behavioral and EEG measures before and after training. The investigators will include 20 young participants and use their baseline as target performance for training in the elderly. 40 elderly participants will be randomly assigned to one of ...

Phase N/A

The Effects of Strawberry Supplementation on Memory and Gait Among Over-weight Older Adults

Previously, the investigators have shown that dietary berry fruit are able to reverse several parameters of brain aging, as well as age-related motor and cognitive deficits when fed to aged rats. They have shown that strawberry, in particular, can reduce oxidative stress and pro-inflammatory signaling in the brain and improve ...

Phase N/A

Auditory Temporal Processes in Aging

This research program in speech perception and auditory psychophysics examines the hypothesis that many of the predominant difficulties in speech understanding of elderly listeners are related to underlying problems in auditory temporal processing. One form of degraded speech that is particularly difficult for elderly listeners to perceive is accented English. ...

Phase N/A

Nitrate Supplementation and Muscle Blood Flow

Dietary nitrate (beetroot juice) is reduced to nitrite and nitric oxide within the digestive system of humans. Nitric oxide exerts potent vasodilator effects, which have been shown to reduce blood pressure and enhance exercise economy in humans. This pressure reducing effect may have implications within the regulation of blood flow ...

Phase N/A

Program for African American Cognition & Exercise

We will randomize 56 older African American adults into 1) a physical activity intervention specifically tailored to older African American or 2) a successful aging group. The 12-week physical activity intervention will consist of group based exercise sessions at a community facility and the successful aging groups will occur at ...

Phase N/A

Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly

Inhibition of the mTOR pathway by rapamycin (RAPA), an immunosuppressive drug used as adjunct therapy in preventing solid organ allograft rejection, enhances longevity in mice. Importantly, RAPA was efficacious even when initiated in relatively old animals. Thus, it has been suggested that RAPA could be used therapeutically in humans to ...

Phase

Age-associated Arterial Dysfunction Western Diet and Aerobic Exercise: Role of the Gut Microbiome

In order to investigate how age-related changes to the gut microbiome, as modulated by Western diet and exercise, influences arterial function in humans, the investigators will capitalize on the plasticity of the gut microbiome to dietary perturbations. A randomized, single-blind, 2x1-week dietary intervention crossover study (with 3 week washout) will ...

Phase N/A