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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (59) clinical trials

Predictors of Cognitive Decline in Normal Aging

Studies of normal aging and mild cognitive impairment (MCI) show that loss of neurons and reduction in size of the hippocampal part of the brain predict a person's conversion from MCI to Alzheimer's disease (AD). Increases in tangle-related abnormal tau proteins, specifically P-tau231, also appear to be related. This study ...

Phase N/A

Effects of Age and Exercise on Blood Pressure Regulation

This study is being done to find out how age, activity level, and the presence of heart disease affect the way the body controls blood pressure. A total of 80 individuals will be recruited for the study, and will consist of two groups: sedentary healthy individuals and those with coronary ...

Phase N/A

Influence of Fitness on Brain and Cognition

Recent studies have shown the encouraging effects of fitness training on human cognition, and brain structure and function. Such effects are of great interest both for what may they tell us about the nature of cognitive and brain aging and also for their public health implications. This study will test ...

Phase N/A

Study of Male Osteoporosis and Aging

Osteoporosis is a disease characterized by decreased bone mass and pathological changes in the microarchitecture of the bones. The clinical significance of osteoporosis is the association with fragility fractures and, consequently, increases in both morbidity and mortality. In men, genetical and life-style factors are known to affect the risk of ...

Phase N/A

Association of Midlife Dietary and Lifestyle Factors on Cardiac Functional Changes in the Elderly

This proposal will investigate how midlife factors in diet and lifestyle affect various aspects of cardiac structure and function related to ageing. The investigators plan to conduct the study among a sub-cohort of 600 participants from the Singapore Chinese Health Study. Comprehensive information on diet and lifestyle factors had been ...

Phase N/A

The Impact of a Physical Activity Program on Biomarkers of Aging During Chemotherapy for Breast Cancer

Our research team has determined that p16INK4a - a biomarker of aging -- increases dramatically during chemotherapy and that p16 levels among patients of similar age are lower among those who exercise. We hypothesize that engagement in physical activity during chemotherapy will have a moderating effect on increases in p16 ...

Phase N/A

Effect of Normal Aging on Language Processing

The purpose of this study is to understand the effect of age on language abilities. The investigators aim at investigating the cerebral modifications that take place in normal aging, at the functional an anatomical level.

Phase N/A

Effect of Aging on Bariatric Surgery-induced Changes in Metabolism and Cognition

With an aging population that is increasingly susceptible to obesity and obesity-related comorbidities including sarcopenia and diabetes, effective and safe treatment options tailored to the needs of older adults are imperative. While medication and lifestyle interventions generally fail to achieve sustained large-scale weight loss, bariatric surgery is the most effective ...

Phase N/A

Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

Under the assumption that aging is caused by dysfunction of specific biological mechanisms, it is reasonable to hypothesize that slowing aging should delay the onset of chronic diseases that typically affect older persons and improve their longevity and quality of life. Indeed, there is emerging evidence that factors associated with ...

Phase N/A

Cadence and Intensity Across the Adult Lifespan

There will be up to two lab visits for CADENCE-ADULTS participants, all of which will be completed in the Physical Activity and Health Lab at University of Massachusetts Amherst. Participation will include: orientation to the experiment, consent, physical examination and testing. The entire research protocol will last between 3.5-4.5 hrs. ...

Phase N/A