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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found (10) clinical trials

The goal of this study is to find out if acarbose, a medicine commonly used to treat diabetes, may have other effects in the body that could slow the aging process. Laboratory experiments have shown that mice treated with acarbose live longer. Scientists believe that acarbose may have “anti-aging” effects ...

Phase

Study of Acarbose in Longevity

Acarbose, an FDA approved drug for the treatment of type 2 diabetes, has known effects on glucose metabolism. Evidence from mice indicates that acarbose may prolong lifespan. In humans, acarbose improves inflammatory markers and reduces cardiovascular events. Consequently, acarbose is of interest in clinical translational aging research since it may ...

Phase

Metformin Induces a Dietary Restriction-like State in Human

Blood samples will be obtained from all individuals. blood lipids, inflammation markers, insulin, glucose, leptin,adiponectin, ala aminotransferase, asp aminotransferase, creatine phosphokinase,lactate dehydrogenase, alkaline phosphatase,bilirubin, cyclo-oxygenase, citrate synthase, renal function, leukocyte telomere length ratio, and telomerase activity will be measured before and after the treatments.Also, hyperinsulinemic-euglycemic clamp will be performed before ...

Phase

Functional Mobility in the Elderly: Influence of Morphological Neuromuscular and Training Parameters

Life expectancy and elderly population are increasing. Health professionals try to provide longevity with good quality of life for this population, through the functional independence maintenance. In this context, physical exercise has an important role, specially the strength training. The ability to produce muscle strength is positively associated with the ...

Phase N/A

Nicotinamide Adenine Dinucleotide and Skeletal Muscle Metabolic Phenotype

-NAD+ sensitive metabolic decline in ageing, including sarcopenia, leads to a reduction in energy metabolism, contribute to chronic inflammation, disposing individuals to metabolic disease and overall decreased later-life health. Prominent metabolic changes include a decline in NAD+ content and deterioration in muscle NAD+ mediated signalling and mitochondrial function, ultimately compromising ...

Phase

Study of Male Osteoporosis and Aging

Osteoporosis is a disease characterized by decreased bone mass and pathological changes in the microarchitecture of the bones. The clinical significance of osteoporosis is the association with fragility fractures and, consequently, increases in both morbidity and mortality. In men, genetical and life-style factors are known to affect the risk of ...

Phase N/A

Effects of High-velocity Resistance Training and Creatine Supplementation in Healthy Aging Males

Purpose and hypothesis: The purpose of this thesis is to compare the effects of HVRT and CR supplementation to HVRT and placebo in healthy aging males. It is hypothesized that HVRT and CR supplementation will increase muscle mass, strength, power and tasks of functionality compared to HVRT and placebo. Participants: ...

Phase

Role of Centrum Silver in Improving Micronutrient Status in Older Men

Older adults are at increased risk of various chronic diseases, in which inadequate levels of vitamins and minerals may play a significant role, including cardiovascular disease, Alzheimer's disease, liver disease, and cancer. Most adults in the United States do not meet the Recommended Dietary Allowance (RDA) or Adequate Intake (AI) ...

Phase N/A

Evaluation of the Impact of Sleep Apnea on Cerebral Volumetry According to Age

The goal of this project is to evaluate the impact of sleep apnea on the brain according to age. Our hypothesis is that adult apneic subjects would present local cerebral modification in the areas implied in cognition and memory, such as the hippocampus or the frontal areas, whereas elderly patients ...

Phase N/A

Strength Training as a Supplemental Therapy of Androgen Deficiency of the Aging Male

The study is 3 groups controlled 12-week study to assess the effect of testosterone replacement therapy (TRT) with strength training (ST) and strength training (ST) for hypogonadal participants without testosterone replacement therapy (NON-TRT) with control healthy eugonadal group, that is also engaged in strength training. Strength training protocol starts one ...

Phase N/A