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Chronic Back Pain Clinical Trials

A listing of Chronic Back Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (133) clinical trials

Cognitive Behavioural Therapy for Insomnia in Chronic Spinal Pain

Modern pain neuroscience has advanced our understanding of chronic spinal pain (CSP). Despite the scientific progresses with regard to the treatment of chronic spinal pain (CSP), current treatments for CSP do not address pain comorbidities like insomnia, an important yet seldom addressed issue. Treatment of CSP mostly still relies on ...

Phase N/A

Medial Branch Block vs Para-spinal Muscle Injection in Patients With Non-specific Chronic Low Back Pain

Pain relief following medial branch block (MBB) might be due to facet joints desensitization and/or myofascial trigger points' desensitization. Patients will be randomized to two groups. The first group receives MBB in one side and paravertebral deep intramuscular (PDI) injection in the other side of the back. Next week the ...

Phase

Evaluating the Role of Neuroinflammation in Low Back Pain

The goal of this research study is to evaluate whether the central nervous systems of those with low back pain are different from those of healthy, pain-free individuals. Specifically, the researchers will test whether "glial cells" (the immune cells of the brain and spinal cord) are more active in patients ...

Phase

Impact of Home Exercise Delivery on Compliance & Outcomes for Musculoskeletal Pain

Patients seeking care for their chronic low back or knee pain will be recruited to participate in a trial investigating the value of different exercise and education prescription strategies as well as strategies to determine the influence of various exercise reminder strategies. On day 1 of enrollment, patients will be ...

Phase N/A

The VIGOR Study - Virtual Immersive Gaming to Optimize Recovery in Low Back Pain

A fundamental clinical problem in individuals with chronic low back pain is the significant alteration in movement patterns that restrict lumbar spine motion. This restriction of lumbar motion is particularly evident in patients with kinesiophobia; that is, a fear of movement due to possible injury or reinjury. For chronic back ...

Phase N/A

Clinical Morphological and Functional Success Predictors Following Lumbar Spinal Surgery in Patients With Chronic Low Back Pain and Degenerative Disorders.

A classification-based approach to identify specific characteristics of patients who seriously suffer from chronic low back pain (CLBP) with referred pain to the legs who are likely to respond to certain interventions has become a research priority in the medical milieu in general and in physical therapy in particularly.While several ...

Phase N/A

Which Exercise for Low Back Pain: A Validation Study

Dr. Macedo and others involved in the proposed research recently conducted a study that investigated whether simple clinical characteristics could identify patients who benefit more from either motor control exercises or graded activity. Motor control exercises (sometimes called lumbar stabilization exercises) and graded activity using the principles of cognitive behavioral ...

Phase N/A

Examining Racial and SocioEconomic Disparities (ERASED) in Chronic Low Back Pain Study

Experimental session 1 Resting Blood Pressure and Body Mass Index will be assessed. Participants will complete the Rapid Estimation of Adult Literacy Measure-Short Form (REALM-SF) to determine health literacy. Participants will complete multiple questionnaires to measure Socioeconomic Status, Clinical Pain Assessment and Depression Scale. All participants will undergo quantitative sensory ...

Phase N/A

Genetic Predisposition for Chronic Non-specific Low Back Pain

The following genes will be investigated: Insertions-/deletions-polymorphism of the angiotensin-converting enzyme (ACE-I/D gene polymorphism; 3 genotypes: ACE-II, ACE-ID, ACE-DD). Anti-adhesive extracellular matrix protein Tenascin-C: gene polymorphism rs2104772 The goals of this study are to investigate whether these genotypes correlate with 1) endurance of back muscles, 2) comorbidities such as asthma ...

Phase N/A

Epigenetic and Molecular Biomarkers in Chronic Low Back Pain and Modic Changes

In the present study the investigators aim to examine the presence of bacteria in the disc and Modic Changes (bone) as well as characterize gene expression patterns and related markers to gain insight into molecular mechanisms that may be important for low back pain (LBP) and the development of Modic ...

Phase N/A