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Influenza Clinical Trials

A listing of Influenza medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (22) clinical trials

Comparison of Three Licensed Influenza Vaccines

This study will evaluate in detail the way that the immune system responds to three different kinds of flu shots that are licensed in the United States.

Phase

Influenza Vaccine To Prevent Adverse Vascular Events (RCT-IVVE)

Cardiovascular disease is a major cause of morbidity and mortality. There is recent evidence that infection due to influenza may precipitate vascular events such as myocardial infarctions and strokes. There is some evidence that influenza vaccination may prevent such events but the data are inconclusive. The investigators propose a randomized ...

Phase

Comparative Clinical Trial of Efficacy and Safety of Ergoferon Versus Oseltamivir in Treatment of Influenza

The overall duration of a patient participation in the trial is 6 days (screening/randomization/therapy onset - day 1; study therapy period - day 1-5; follow-up period - day 6).

Phase

Evaluating The Safety And Clinical Efficacy Of Elderberry Extract In Patients With Influenza

This research is being done to determine if an extract of cooked elderberries will help decrease the duration and severity of influenza symptoms in patients with confirmed influenza. Involvement in this study requires an initial patient screening at the time of their Emergency Department visit in order to confirm eligibility ...

Phase

The Role of CD4+ Memory Phenotype Memory and Effector T Cells in Vaccination and Infection

This is a Phase IV study of up to 100 healthy children, ages 6 months to 10 years of age, who will receive either Flumist live, attenuated influenza virus vaccine, quadrivalent (LAIV4) or the current Fluzone inactivated influenza vaccine, quadrivalent (IIV4). The volunteers will be enrolled into one of 3 ...

Phase

A Study of Intranasal Live Attenuated Influenza Vaccine Immunogenicity and Associations With the Nasopharyngeal Microbiome Among Children in the Gambia

Purpose The overall goal of this study is to conduct at detailed immunogenicity study of intranasal live attenuated influenza vaccine (LAIV; Nasovac-S, Serum Institute of India Pvt. Ltd.), including identification of early molecular signatures associated with a robust mucosal immune response. In addition, the study team will explore whether the ...

Phase

Evaluation of the Effects of Age Prior Exposure and Previous Vaccination on B Cell Response to Influenza Vaccine in Healthy Adults and Children

The study will be designed as a prospective surveillance of the immune response to seasonal influenza vaccination in 240 healthy children and adults ages 9 and over. Study duration will be 5 years, with a participant duration of 6 months. Subjects will receive Fluarix (GSK) quadrivalent inactivated influenza vaccine, at ...

Phase

Adjuvanted Inactivated Vaccine Versus Inactivated Influenza Vaccine in Hutterite Children

This study is a randomized controlled trial (RCT) comparing adjuvanted influenza vaccine (AV) to unadjuvanted inactivated influenza vaccine (IIV). Children in Hutterite colonies in Alberta and Saskatchewan will receive AV or IIV. The goal of this study is to determine whether the AV vaccine, can provide increased community-wide protection.

Phase

Analysis of Bone Marrow and Blood B Cell Immune Responses to Influenza Vaccination

This is a Phase IV open label and single arm study enrolling up to 55 healthy males and non-pregnant females in a single site, 18-49 years old, inclusive. The primary objective of this study is designed to assess the humoral response to influenza vaccination and the longevity of humoral immunity ...

Phase

Study of Immune Responses to Influenza Vaccination

Better understanding of the immune responses to influenza vaccination is needed in order to understand situations of poor vaccine response. Adults will receive influenza vaccination and then have peripheral blood drawn at pre-defined intervals in order to study the lymphocyte responses.

Phase