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Circulation Disorders Clinical Trials

A listing of Circulation Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (43) clinical trials

Evaluation of the Pharmacokinetics of Caspofungin in ICU Patients

Although the pharmacokinetics of Caspofungin has been studied in healthy subjects and patients, only a few studies have been performed in critically-ill patients. In these patients several factors, including sepsis, shock, increased distribution volume, hepatic dysfunction and hypoalbuminemia may result in dramatic changes in antibiotic concentrations and pharmacokinetics. Caspofungin pharmacokinetic ...

Phase N/A

Effects of Hemodynamic Monitoring Using the ImaCor Single Use Transesophageal Echocardiography Probe in Critically Ill Patients

Background Hemodynamic management of critically ill patients is a constant challenge in the intensive care unit (ICU). Commonly used monitoring parameters to guide hemodynamic management generally consist of measurements of pressures (systemic and pulmonary artery pressures, cardiac filling pressures) and flow (cardiac output measurements using a thermodilution method). However, cardiac ...

Phase N/A

Natural History of Stroke: Cause and Development

OBJECTIVE: This is a natural history/disease pathogenesis protocol for evaluation of patients with or at risk for acute stroke, transient ischemic attack (TIA), or other disturbances of cerebrovascular circulation. The purpose of this protocol is to generate natural history data to serve as the basis for future hypothesis-driven protocols as ...

Phase N/A

Stroke and Cerebrovascular Diseases Registry

Stroke is the fifth cause of all-cause mortality in US Early identification and treatment not only prevent mortality but also morbidity. Recent advancement in the imaging and diagnostic technique and novel therapeutic modalities has dramatically helped to downgrade stroke from the list of top mortality index in the last ...

Phase N/A

Tissue Near InfraRed Spectroscopy (NIRS) in Critically Ill Patients

Project Overview: This project is focused on the early diagnosis and management of septic shock using tissue near infrared spectroscopy (tNIRS) for continuous and non-invasive assessment of microcirculatory vasoreactivity as a diagnostic and prognostic indicator in critically ill patients. A novel aspect of this study is that point of entry ...

Phase N/A

Point of Care Ultrasonography In The Management of Undifferentiated Shock: A Pilot Randomized Controlled Trial

This project aims to determine the feasibility of conducting a randomized controlled trial investigating point of care ultrasound guided resuscitation compared with usual care in the management of undifferentiated shock at the Critical Care Trauma Centre (CCTC) in London Health Science Centre (LHSC).

Phase N/A

The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN)

The purpose of the study is to test whether the health care provider access and training in CERTAIN (Checklist for Early Recognition and Treatment of Acute Illness), would facilitate timely and error free best-practice delivery and minimize preventable death and costly complications in critically ill patients.

Phase N/A

Population-based Brest Stroke Registry

The main objective of Brest Stroke Registry is to regroup all confirmed cases of stroke over a defined geographical zone in order to calculate an incidence. There are three prospective medium-term goals: In respect with public health epidemiology: To obtain incidence data and evaluate the regional and international divergences To ...

Phase N/A

Oxidative Stress in Critical Ill Patients in Surgical Intensive Care Unit

In clinical practice, the oxidative stress is related to circulatory shock, sepsis, acute lung injury, and acute respiratory distress syndrome. There are some questions on the oxidative stress of the critical illness. First, the investigators want to search out the effects of the past history, smoking, alcohol drinking, use of ...


Evaluation of the Quality of the NovoSeven (rFVIIa) Tratment Practice at Rigshospitalet Copenhagen University Hospital

The purpose is to evaluate and improve NovoSeven treatment practice done according to our guidelines

Phase N/A