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Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (688) clinical trials

18F-Flutemetamol and Plaque Vulnerability

Rationale: Amyloid beta (Ab) is mainly known for its role in Alzheimer's disease (AD) pathology. However, Ab seems not only to be involved in AD pathology, but also in atherosclerosis, which might explain the remarkable similarities in risk factors between these two pathologies. In vitro studies suggest that a major ...

Phase

Use of Glidesheath Slender to Reduce Radial Artery Occlusion and Vascular Access Site Complications Following Transradial Coronary Angiography

Based on previously reported studies the rates of radial artery occlusion using a standard 6 Fr. sheath is around 5-10%, compared to the single feasibility study of the Glidesheath Slender by Aminian et al (see reference in the citations), the rate of radial artery occlusion was reported 0.88%. This study ...

Phase N/A

ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study for the Patients With ACS

The drug-eluting stents (DESs) are currently used in the majority of percutaneous coronary intervention (PCI) procedures. On the other hand, the problems of the first-generation DES (late adverse events, such as very late stent thrombosis) have been pointed out. Dual antiplatelet therapy (DAPT) has become a standard regimen after DES ...

Phase

Hemodynamics and Autonomic and Cognitive Performance After Carotid Revascularization Procedures

Hypothesis and Significance: Late clinical outcome and prognosis after CAS may be inferior to that after CEA in terms of autonomic modulation, hemodynamic remodeling, and cognitive function. Specific Aim: 1) To compare the impact of CEA and CAS on long-term post-operative baroreceptor function and on cognitive brain function, and analyze ...

Phase N/A

RESOLUTE ONYX China Single Arm Study

This study is a pre-Market, prospective, multi-center, single arm trial. Subjects will be enrolled and followed through 5 Years (screen, implant procedure(including post-procedure assessment),30-Day, 6 Months, 9 Months-subjects implanted with fringe size, and annual assessments from 1-5 years).

Phase N/A

Coronary Artery Disease Progression in Patients With Prediabetes

Patients undergoing PCI and IVUS pullback for the target vessel will be enrolled in a prospective study. Before PCI and at 24 month follow up fasting blood will be collected for glucose, HbA1c, insulin, C peptide, lipid profile assessment and the homeostasis model assessment of insulin resistance (HOMA-IR) calculation. Patients' ...

Phase

Dynamic Computed Tomography Myocardial Perfusion Imaging for Detection of Coronary Artery Disease

This will be a prospective study comparing the low-dose dynamic vs. static CTP combined with the CTA for detecting hemodynamically significant coronary artery stenosis. The aim of the study is to assess the feasibility, safety and accuracy of low-dose dynamic CTP following CTA. The study will enroll patients who have ...

Phase N/A

Miniaturized Extracorporeal Circulation Study

Blood samples will be obtained at the following time points: T0; preoperative after induction of anaesthesia (after insertion of central venous line) T1; after weaning of the ECC prior to protaminization T2; 10 minutes after full protaminization T3; six hours after the end of the ECC T4; 1. postoperative day ...

Phase N/A

Implementation of CYP2C19 Genotyping to Guide Antiplatelet Therapy

Dual antiplatelet therapy with aspirin and a P2Y12 receptor inhibitor represents the standard of care treatment for the prevention of major adverse cardiovascular events in patients undergoing percutaneous coronary intervention (PCI). Currently, 3 oral P2Y12 receptor inhibitors (clopidogrel, prasugrel, and ticagrelor) are available for clinical use. Clopidogrel remains the most ...

Phase N/A

The CAROLE (CArdiac Related Oncologic Late Effects) Study

Background: Within the United States, there are an estimated 3.1 million women alive who have been diagnosed with invasive breast cancer, and approximately 56% of them have received radiation. Worldwide, there are 1.4 million diagnosed annually and, in 2012, it was the most commonly diagnosed cancer in women. As patients ...

Phase N/A