Search Medical Condition
Please enter condition
Please choose location from dropdown

Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (709) clinical trials

People with Atherosclerotic Lesions are asked to participate in a research study being conducted by Montefiore Medical Center.

Phase N/A

To evaluate the effectiveness of MicroVention Carotid Stent System used in conjunction with the Nanoparasol embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy.  The stent is a self-expanding implant with a rapid exchange delivery catheter. The Nanoparasol ...

Phase

This is a prospective, randomized one to one (1:1), multi-center trial designed to evaluate vessel preparation with Orbital Atherectomy (OA) compared to conventional balloon angioplasty technique prior to stent implantation for the treatment of severely calcified coronary artery lesions.  

Phase N/A

Research study to compare surgery, either a stent, or endarterectomy, and/or intensive medical management. Carotid arteries are the main arteries feeding your brain. The narrowing increases your risk of having a stroke. The narrowing is caused by a thickened area called a plaque.  

Phase N/A

Combined Use of Multiple Biomarkers With Stress Testing to Detect Coronary Artery Disease

The COMBAT-CAD Study is an observational study with the aim to improve the diagnostic accuracy by a combination of stress testing with sensitive and specific biomarkers in detecting coronary artery disease or its progress. The main subjects are all patients with CAD or suspicion of CAD sent to the University ...

Phase N/A

Assessment of Atherosclerotic Plaque Characteristics Change by DCE-MRI With Alirocumab

Acute ischemic events caused by atherosclerosis cardiovascular disease (ASCVD) are primarily due to plaque rupture/erosion determined by plaque morphologic characteristics, local composition and inflammation, which can be directly assessed using magnetic resonance imaging (MRI). Prospective carotid MRI studies have demonstrated: (1) plaques with thin or ruptured cap, intraplaque hemorrhage (IPH), ...

Phase

Pilot Study of Pre-Ischemic Conditioning for Intracranial Atherosclerosis

In this prospective randomized pilot study, 10 eligible high-risk subjects with ICAS will be randomized to RLIC (bilateral upper extremity daily for 30 days) plus medical management (n=5) or medical management alone (n=5). The medical management, which is the standard of care, will be started at study enrollment and continued ...

Phase N/A

Exercise Arterial Cross-Talk Modulation and Inflammation in an Ageing Population

In the cross-sectional part the investigators analyze physical fitness, vascular health and further outcomes in a healthy older active, a healthy older sedentary and a obese sedentary group with increased cardiovascular risk. The investigators will analyze large and small artery function, physical fitness and activity as well as inflammatory parameters ...

Phase N/A

EUROASPIRE V Survey on Cardiovascular Disease Prevention and Diabetes

A fifth European survey of Cardiovascular Disease prevention and Diabetes (EUROASPIRE V) is being conducted in 2016-2018 under the auspices of the European Society of Cardiology, EURObservational Research Programme. This fifth survey incorporate an assessment of dysglycaemia and kidney function in all patients. As in the previous EUROASPIRE surveys this ...

Phase N/A

Statin Recapture Therapy Before Coronary Artery Bypass Grafting

Patients with coronary artery disease (CAD) requiring coronary artery bypass grafting (CABG) are still at significant risk for postoperative major adverse cardiocerebral events (15% MACCE rate), with 3% of patients dying within 30 days of surgery. Recent clinical evidence shows that cardioprotection in patients receiving chronic statin treatment can be ...

Phase