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Atherosclerosis Clinical Trials

A listing of Atherosclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (7) clinical trials

Evaluation of CTCA in Assessing Plaque Pathology and Physiology

Cumulative evidence has demonstrated that plaque characteristics and vessel physiology are able to detect vulnerable plaques and identify high-risk individuals that are likely to suffer a cardiovascular event. The in vivo assessment of plaque morphology was traditionally performed using intravascular imaging techniques; however these modalities have significant limitations as: 1) ...

Phase N/A

Study to Evaluate the QT / QTc Interval Prolongation Potential of Vericiguat

The objective of this study is to evaluate the effect of multiple doses of vericiguat on the QTc interval in patients with stable CAD (coronary artery disease).

Phase

Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI

The Sleep and Stent II is a cross-sectional study of patients who have undergone PCI for coronary artery disease. A total of 200 adult patients who have undergone clinically indicated PCI between 6 and 36 months ago are eligible. The study involves the 2 national heart centers in Singapore. The ...

Phase N/A

The Efficacy of Alirocumab for Thin-cap fIbroatheroma in Patients With Coronary Artery Disease Estimated by Optical Coherence Tomography

The investigators investigate to evaluate the efficacy of alirocumab for vulnerable plaque. The investigators enrolled the patient with standard statin therapy who were detected vulnerable plaque by optical coherence tomography, and categorized into two group; the patients with alirocumab and rosuvastatin were categorized alirocumab therapy group, and the patients with ...

Phase

Pilot Study-Magnetic Resonance Imaging for Global Atherosclerosis Risk Assessment

There are up to 2 study visits in this study. During the first visit, the investigators will obtain non-contrast MRI (carotid, coronary, and femoral) in 20 subjects with known coronary atherosclerosis but varying degrees of CVD risk. 5 asymptomatic subjects with lower CVD risk (recent coronary artery calcium score [CACS] ...

Phase N/A

Prasugrel Versus Ticagrelor in Patients With CYP2C19 Loss-of-function: a Validation Study

Therapeutic inhibition of platelet activation is essential for the management of ischemic cardiovascular disease. The use of platelet adenosine diphosphate (ADP) P2Y12 receptor antagonists (clopidogrel, prasugrel, and ticagrelor) in addition to aspirin are associated with a decrease in cardiovascular events in high-risk coronary artery disease (CAD) patients. Clopidogrel is the ...

Phase

Connected Rehabilitation: an Alternative to Conventional Cardiovascular Rehabilitation?

Cardiovascular rehabilitation (CVR) has major beneficial effects by improving physical capacity, accelerating return to activities and reinsertion and reducing mortality. It associates reconditioning to effort and therapeutic education for the optimal control of " risk factors ". It corresponds to a global approach to patients, thus counterbalancing the tendency to ...

Phase N/A