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Allergy Clinical Trials

A listing of Allergy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (133) clinical trials

The Effect of Per Oral Immunotherapy in Severe Milk Peanut and Egg Allergy in Adults

30 patients with milk allergy (at least 18 year olds), 30 patients with peanut allergy and 30 patients with egg allergy are treated with OIT. The diagnosis of food allergy is verified with positive history, skin prick test, egg and milk allergen specific IgE antibodies. In addition, food allergy is ...

Phase N/A

A Randomized Prospective Clinical Trial of Fel d 1 Peptide Immunotherapy

Cat-PAD is an experimental cat allergy vaccine and has been studied to determine if it can reduce symptom scores of participants exposed to cat allergen. To study how the vaccine causes changes in the immune system, the researchers plan to evaluate changes in the blood (genes and proteins) and urine ...

Phase

Probiotic Supplementation in Breastfed Newborn Infants

The proposed phase I clinical trial is a parallel-group, placebo-controlled, randomized, double-blind ascending dose study of dietary supplementation with Bifidobacterium longum subsp. infantis (B. infantis) in healthy breastfed infants to evaluate its safety as well as determine the pharmacologically effective dose (ED) of B. infantis producing at least 50% gut ...

Phase

Effect of Mediterranean Diet During Pregnancy on Gut Microbiota and on the Epigenetics

Food allergies (AA) are adverse reactions to food. Over the last decade, the AA scenario has changed profoundly. In many countries, there has been a significant increase in the prevalence, persistence and severity of AAs and a consequent increase in the socio-economic impact associated with these conditions. For these reasons, ...

Phase N/A

Pharmacokinetics of Intramuscular Adrenaline in Food--Allergic Teenagers

Food allergy affects up to 2% of adults and 8% of children in the United Kingdom (UK), and is a major public health issue. It is the commonest cause of life-threatening allergic reactions (anaphylaxis), which can be fatal. Adrenaline (epinephrine) auto-injector (AAI) devices are the first-line treatment for anaphylaxis, yet ...

Phase

Development of Diagnostic Pathway for Teicoplanin Allergy

Teicoplanin is an antibiotic used very commonly to prevent infection during surgery. Its use has expanded rapidly in the last few years, with around 18,500 doses administered in Leeds Teaching Hospitals NHS Trust alone, in 2014-15. Unfortunately, anaphylaxis (a severe allergic reaction) to the drug appears to be increasing. These ...

Phase N/A

Efficacy and Safety of PR022 Topical Gel to Treat Mild-to-Moderate Atopic Dermatitis

The purpose of this study is to determine whether PR022 Topical Gels are safe and effective treatments for mild-to-moderate atopic dermatitis (AD).

Phase

Allergic Rhinitis Immunotherapy and Vitamin d

Vitamin D as adjuvant to subcutaneous specific immunotherapy in patients with allergic rhinitis BACKGROUND Allergic diseases are considered the pandemic of the 21 century. Allergic rhinitis (AR) is the most common with an overall prevalence of 4 to 40% in the world. In Latin America, it is a common chronic ...

Phase

Precision Allergy: Separate Allergies to Male and Female Dogs

A new male-specific dog-allergen-component has been found (Can f 5) which indicates possible differences in allergic reactions to male and female dogs. This has not yet been tested in real life. The aim is to test if sensitization only to the male-dog specific allergen-component, Can f 5, results in a ...

Phase N/A

Inhibition of Anaphylaxis by Ibrutinib

This is open-label study designed to determine the fewest doses and shortest length of time, from two days to up to 7 days, needed for ibrutinib to fully inhibit tests for food allergy, and to determine the length of persistence of efficacy after the drug is stopped.

Phase