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Bone Fractures Clinical Trials

A listing of Bone Fractures medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (57) clinical trials

Lithium for Fracture Treatment

Despite the success of traditional treatments for broken bones (surgery, immobilization, or both) 10% of fractures do not heal or take longer than normal to heal. This can have a significant effect on a patient's function and productivity, as well as on healthcare expenditures. Very few advances in fracture healing ...

Phase

Comparative Volumetric Assessment of Alveolar Ridge Preservation Utilizing Different Bone Grafting Materials

This study is intended to provide statistically robust evidence that Symbios Demineralized Cortical-cancellous granule mix, Symbios OsteoGraf LD-300, and OsteoGraf/N-300 combined with Symbios OsteoShield Collagen Resorbable Membrane can adequately support the alveolus during ridge augmentation procedures, reducing the dimensional changes of both the alveolus and the overlying soft tissues. Additionally, ...

Phase N/A

Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)

Although close to 85% of frail women in long-term care (LTC) facilities have osteoporosis and the risk of osteoporotic fractures is nearly 10 times that of community dwelling elderly, few are treated and studies are scarce. It is postulated that in frail, LTC women an annual infusion of zoledronic acid, ...

Phase

Wild-type Reovirus in Combination With Carfilzomib and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

PRIMARY OBJECTIVES: I. Determine safety and tolerability, and define the maximum tolerated dose of reolysin (wild-type reovirus), carfilzomib and dexamethasone in patients with relapsed multiple myeloma. II. Obtain evidence of reovirus entry into myeloma cells via localization of reoviral ribonucleic acid (RNA) in multiple myeloma (MM) cells (in situ hybridization ...

Phase

Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children

Long-bone fractures are a very common complain for visits in paediatric emergency departments. Since these fractures are often very painful, morphine is considered the cornerstone treatment in case of severe pain. Very few data are available concerning the assessment of analgesic treatment in this condition. In our previous study, less ...

Phase

Reamer Irrigator Aspirator (RIA) vs Autogenous Iliac Crest Bone Graft (AICBG) for the Treatment of Non-unions

All subjects will be pre-screened by the treating physician. Subjects who present with a nonunion of a long bone will be invited to speak to the research coordinator regarding the study. An internet based randomization system will be used to allocate subjects to treatment groups. Participating sites will be given ...

Phase N/A

Data Collection Study for the Spectrum Dynamics Multi-purpose CZT SPECT Camera

The Spectrum Dynamics Multi-purpose CZT SPECT camera is a whole body SPECT (single photon emission computed tomography) scanner which utilises solid-state cadmium zinc telluride (CZT) detectors to visualise injected, or otherwise introduced, radioactivity in the human body. The CZT SPECT camera detects the location and distribution of gamma-emitting radionuclides in ...

Phase N/A

Enhancement of Bone Regeneration and Healing in the Extremities by the Use of Autologous BonoFill-II

Primary Endpoint: To establish that the transplantation of BonoFill-II into bone defect/gap is safe under the following conditions: No treatment-related appearance of heterotrophic bone ossification No excessive bone formation at the transplantation sites No abnormalities in the treated sites Secondary Endpoint: To establish that the transplantation of BonoFill-II into bone ...

Phase

A Skills-Based Program Delivered Via Videoconferencing in Patients With Acute Musculoskeletal Trauma

The aims of this pilot randomized controlled trial are to compare the effect of a manualized skills-building program against usual care in preventing the development of chronic pain and disability following acute musculoskeletal injury in at-risk patients, and to test the feasibility and acceptability for delivery through live videoconferencing.

Phase N/A

CMF Bone Stimulation as Adjunct to Surgical Treatment of Ankle Fractures

The OL1000 is intended to be used as a non-invasive adjunctive treatment for adult males or females that have sustained a closed, unstable ankle fracture that requires surgical treatment for stabilization. The initiation of the adjunctive treatment is to begin within 11 days of surgical stabilization.

Phase N/A