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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (20) clinical trials

Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation: A Personalized Approach

This study will evaluate the anti-inflammatory effects and antidepressant efficacy and tolerability of EPA versus placebo in the treatment of MDD. The study design is a randomized, placebo-controlled, double-blind parallel-group dose-finding 12 week outpatient clinical trial. The study population will consist of outpatients who are overweight and suffer from MDD, ...


Dialogical and Narrative Processes in Couple Therapy for Depression

In each of these research centres qualified family therapists will conduct the couple therapy in case of depressed patients in a team of two therapists. To be a responsible therapist in this study the minimum criterion is three years specialist- level family therapy training and thus a qualification as psychotherapist ...


Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Bipolar Disorder

The primary goals of this proof of concept study are to determine the effectiveness, safety and tolerability of FMT in adults with BD depression. Objective 1: To evaluate the effectiveness of the combination of a currently accepted approved therapy for BD depression + FMT in individuals with BD depression. This ...


Action of Ketamine in Treatment-Resistant Depression

Major depressive disorder (MDD) carries worldwide the largest burden of diseases among mental, neurological, and substance-use disorders measured in Disability Adjusted Life Years (DALYs), according to the World Health Organization (WHO).1 In turn, MDD has the highest DALYs in middle to high income countries, with ischemic cardiac diseases being second.2 ...


CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery)

If the patients have not decided on which pain relief method to be used, and would like to take part in this study, they will be assigned to either epidural or non-epidural pain relief for labour based on the study randomization result. Blood samples will be drawn to study the ...


Hemofiltration for Respiratory Failure After Bone Marrow Transplantation

For children undergoing bone marrow transplantation, respiratory failure carries mortality expectations well above 60%. The researchers have published preliminary evidence that continuous hemofiltration may greatly improve survival, if filtration is begun when the child first fulfills clinical criteria for ARDS. This is a departure from standard practice, as hemofiltration is ...


Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale

The objective of the present study is to evaluate the effectiveness of postnatal depression screening by comparing the mental health outcome (at 6 months postpartum) of mothers under the Edinburgh Postnatal Depression Scale (EPDS) screening programme versus usual clinical practice (usual practice), using randomized controlled trial design. With the use ...


Study on the Use of Low Dose Ketamine After Gastric Bypass and Gastrectomy

This is a randomized, double-blind, placebo-controlled, two-arm parallel, single-center study. One hundred subjects (50 in each arm) will be enrolled. Subjects, between the ages 18 and 65, undergoing laparoscopic gastric bypass or sleeve gastrectomy will be recruited and consented during the preadmission visit prior to surgery. Eligible subjects will be ...


Study Testing if Fast or Slow rTMS is Better for the Treatment of Posttraumatic Stress Disorder (PTSD)

Objectives: The primary objective is to test whether right prefrontal cortex low frequency 1 Hz rTMS versus right prefrontal high frequency 10 Hz rTMS provides a significantly greater improvement in function as measured by IPF score and PTSD symptoms as measured with CAPS score. The secondary objectives include: one, testing ...


Fluid Restriction Keeps Children Dry

Rationale: Fluid overload is a common complication in children who are admitted to the pediatric intensive care for mechanical ventilation. Acute lung infection is a frequent cause for admission to the PICU and forms an uniform group with a single organ failure. In these critically ill children, fluid overload is ...