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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (94) clinical trials

The study is trying to understand what causes bipolar disorder and how medications treat bipolar depression. If you participate, you will have two different brain scans (an MRI and a PET scan) and antidepressant treatment for free. We will then be able to see whether information on the brain scans ...

Phase

The purpose of this study is to evaluate the efficacy of vortioxetine treatment period in the prevention of relapse in participants with major depressive disorder (MDD).

Phase

This study is a randomized, double-blind, placebo-controlled study to evaluate 3 fixed doses (5, 10, and 20 mg oral tablets) of vortioxetine once daily in the prevention of relapse in adult subjects with major depressive disorder (MDD) who have responded to acute treatment with vortioxetine.

Phase

A clinical study designed to collect information on the safety and efficacy of an anti-depressant to treat depression, OCD, or anxiety with or without CBT therapy.

Phase

Montefiore Medical Center is seeking patients with major depressive disorder (MDD) between the ages of 18 and 65 to participate in a new depression research study. Dr. Jonathan Alpert is conducting this research to assess if the combination of brexpiprazole and intranasal ketamine can safely and effectively treat depression symptoms ...

Phase

The purpose of this study is to compare the accuracy and reliability of self-administered memory and thinking skills tests taken on an iPad tablet against the same tests administered by a doctor. The method for administering these tests could be used in future clinical studies when a study medication is ...

Phase

Advancing Personalized Antidepressant Treatment Using PET/MRI

Aim 1: Determine a Pretreatment Marker of SSRI Effectiveness Using PET. With the goal of reducing MDD burden, many studies have assessed the utility of FDG-PET in antidepressant treatment prediction. However, due to the limitations listed above, there is no consensus on which brain regions are predictive of treatment efficacy. ...

Phase

Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators

Caregiver will be consented for his/her and the child's participation. The child will assent to participate before study procedures begin. The proposed study will last 52 weeks and consist of study visits every 4 weeks (14 visits total). Screening (roughly 5 mins): 2 item Self-Report Screening Tool for Depression (2-SRSD) ...

Phase

CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)

Oral Abilify (aripiprazole) is effective in the treatment of patients with BD when prescribed as an acute anti-manic agent and for the maintenance treatment of bipolar disorder. Abilify Maintena is an intramuscular (IM) depot formulation of oral aripiprazole (Abilify). Abilify Maintena appears to be as effective as standard oral Abilify ...

Phase

The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major Depression

The study will be a double blinded, randomized controlled trial. The medications will be administered orally. The sample size will be 40 participants, 20 in the treatment group and 20 in the control group. The study period will be 4 weeks. Eligible participants will have major depression by history for ...

Phase