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Depression Clinical Trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (31) clinical trials

The PPD-202 Trial is a multi-center, randomized, double-blind, parallel-group, placebo-controlled study evaluating the efficacy, safety and pharmacokinetics of SAGE-547 Injection in the treatment of adult female subjects with severe postpartum depression.

Phase

The purpose of this study is to evaluate the efficacy of sirukumab as adjunctive treatment to antidepressant therapy, where sirukumab is measured over a 12 week study period for treatment of depression symptoms.

Phase

A clinical research study to evaluate the safety, effectiveness and tolerability of an investigational drug for individuals with Major Depressive Disorder.

Phase

To assess, in subjects with MDD who have had an inadequate response to current antidepressant therapy with an SSRI or SNRI, the efficacy of flexibly dosed JNJ-42847922 (20 mg or 40 mg) compared to flexibly dosed quetiapine XR (150 mg or 300 mg) as adjunctive therapy to an antidepressant drug ...

Phase

This research study examines the safety and effectiveness of an investigational drug in adult subjects with major depressive disorder who have responded inadequately to antidepressant therapy. This study is approximately 12 weeks.  The first visit will consist of a physical exam, blood draw, ECG, urine drug screen and psychiatric assessments. 

Phase

Prevention of Depression With Omega-3 Fatty Acids in Chronic Carriers of Hepatitis C Treated With Interferon Alpha.

Omega-3 fatty acids are known as an alternative treatment for different conditions, including mental conditions, such as depression. We assume that combining omega-3 with the treatment by interferon alpha may prevent the development of depression, which is quite a common side effect of the interferon alpha.

Phase

rTMS in the Treatment of Bipolar Depression

Bipolar affective disorder is a serious mental illness with significant mortality and morbidity [1]. Some estimates of prevalence in Western populations are as high as 6.4% [2]. The depressive aspect of bipolar disorder is often overlooked, possibly due to its less dramatic nature, despite its significant impact on the lives ...

Phase

Antidepressant Effect of Theta-Burst rTMS

The aim of this study is to evaluate the safety and efficacy of theta-burst rTMS in patients with major depression. Patients will be randomized to receive ether left-sided intermittent theta-burst rTMS or rigt-sided continuous theta-burst rTMS or sham theta-burst rTMS over two weeks period with an option for an additional ...

Phase

Detection and Treatment of Depression in Patients Admitted to the General Hospital

Depression is a common disorder among patients with a somatic illness admitted to the general hospital. Patients with depression do worse in terms of their somatic symptoms or functioning that those without depression. They also stay in the hospital for longer. That is the reason that we are interested to ...

Phase

TMS in the Treatment of the Sequelae of Closed Brain Injury

It is plausible to propose that the same treatment paradigm may result in an improvement in mood and cognition with the possibility that these changes will be self reinforcing resulting in enhanced quality of life and reduced service demands. The proposal for the use of rTMS in the treatment of ...

Phase