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Esophageal Cancer Clinical Trials

A listing of Esophageal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (17) clinical trials

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Patients and Healthy Participants Undergoing Colonoscopy Endoscopy or Surgery

OBJECTIVES: - Identify new potential biomarkers of increased gastrointestinal cancer risk using tissue and biofluid samples from patients and healthy volunteers undergoing colonoscopy, endoscopy, or surgery. - Develop new screening strategies based on substances found in tissue and biofluid samples. OUTLINE: This is a multicenter study. Patients and healthy volunteers ...

Phase N/A

Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer Head and Neck Cancer or Aerodigestive Tract Cancer and in Normal Volunteers

OBJECTIVES: Primary - Determine intermediate biomarkers of premalignant respiratory epithelial lesions, such as genetic mutations or altered growth factor expression, in patients with dysplasia of the respiratory epithelium or lung cancer, head and neck cancer, or aerodigestive tract cancer. Secondary - Establish a tissue repository of normal and dysplastic respiratory ...

Phase N/A

Photodynamic Therapy (PDT) Oncology Registry

Participating centers will need to describe its own mechanism for patient identification and eligibility screening. A data manager, identified by the Principal Investigator at each participating center, will screen all patients for eligibility. Appointment, diagnosis and treatment data will be reviewed using information such as clinic records, appointment lists, pathology ...

Phase N/A

Esophageal Cancer Genetics Studies

The overall goal of this project is to understand the role of genetics in the etiology and prevention of upper gastrointestinal cancer, primarily esophageal cancer, but also cancers of the gastric cardia and body. Esophageal cancer is the fourth most common cause of cancer death in China and the seventh ...

Phase N/A

Early Detection of Esophageal Cancer

Esophageal cancer is a common malignancy with a very poor prognosis. The principal reason for its poor prognosis is that most tumors are asymptomatic and go undetected until they have spread beyond the esophageal wall and are unresectable. Significant reduction in esophageal cancer mortality will require successful strategies to diagnose ...

Phase N/A

Predicting Risk of Cancer in Barrett's Esophagus

Patients with Barrett's esophagus (BE) have an increased risk of esophageal adenocarcinoma which is 40-125 fold higher than in the general population. However, the current techniques of detecting dysplasia and observing abnormal p53 immunohistochemical staining are not accurate or reliable methods for determining which BE patients will progress to cancer. ...

Phase N/A

Studying Genes for Barrett's Esophagus in Brothers and Sisters

OBJECTIVES: Primary - To investigate the familial incidence of heartburn and Barrett's esophagus in first and second degree relatives of patients with Barrett's esophagus in the United Kingdom. - To determine susceptibility genes for Barrett's esophagus in affected sibling pairs. - To examine gene-environment interactions, such as smoking, alcohol, and ...

Phase N/A

Identifying Genetic Markers for Esophageal Cancer and Stomach Cancer in Chinese Populations

OBJECTIVES: - Examine the role of genetics in the etiology and prevention of esophageal and gastric cancer in Chinese populations. - Identify potential early genetic markers of susceptibility for esophageal and gastric cancer. OUTLINE: - Tumor/nontumor study: Patients complete a 1-hour questionnaire about their general background, medical history, family history ...

Phase N/A

Barrett's Esophagus Related Neoplasia (BERN) Project

B. BACKGROUND AND SIGNIFICANCE Burden of disease Barrett's esophagus (BE) is an acquired condition resulting from chronic gastroesophageal reflux disease and is a well recognized pre-malignant condition for the development of esophageal adenocarcinoma (EAC) (1, 2). BE is defined as the displacement of the squamocolumnar junction proximal to the gastroesophageal ...

Phase N/A

Study of Genes and Environment in Patients With Cancer in East Anglia Trent or West Midlands Regions of the United Kingdom

OBJECTIVES: - To obtain epidemiological information and biological material on a population-based series of cancer cases, including malignant melanoma, lymphoma, bladder, kidney, esophageal, and pancreatic cancer, and brain tumors. - Identify novel cancer susceptibility genes, by comparison of genotype frequencies in cases with the corresponding frequencies in large control series. ...

Phase N/A