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Head and Neck Cancer Clinical Trials

A listing of Head and Neck Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (544) clinical trials

Oncogeriatric Intervention and Follow-up at Home

Cancer of the head and neck (HNC), lung (LC), upper gastrointestinal channel (CUGI) and colo-rectal cancer (CRC) accounts for approximately 40% of cancer incidence in elderly people (defined as 70 years) in Denmark (DK). The four cancers account for more than 50% of the annual cancer-related deaths in DK. Incidence ...

Phase N/A

Pembrolizumab in Combination With Anti-platelet Therapy for Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

The purpose of this study is to see if anti-platelet therapy combined with anti-PD-1 immunotherapy can cause a more favorable immunologic response thatn with immunotherapy alone in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.


Combination of Hyperthermia and Concurrent Chemoradiotherapy (CCRT) for Recurrent Head and Neck Cancer

Patients will be treated with radiotherapy with 50Gy/22fx/6 weeks, plus hyperthermia for 40 minutes within 2hr after irradiation, with maximum temperature setted on 42 0.5 as upper limit, once a week since the 1st week of radiation for a total of 6 times. The regimen of concurrent chemotherapy will be ...


ADXS 11-001 Vaccination Prior to Robotic Surgery HPV-Positive Oropharyngeal Cancer

This is an investigator-initiated prospective clinical study of patients with stage I-IV squamous cell carcinoma of the oropharynx (OPSCC) who are to undergo ablative transoral robotic surgery (TORS). There is a vaccination group and a control group in this study. Subjects in the control group will not receive the vaccination ...


Interest of Pregabalin (Lyrica) on the Treatment of Reflex Earache in Head and Neck Cancer.

Referred otalgia is one of the symptoms of oropharynx and hypopharynx cancer. It can be primary (otodynia) or secondary (referred otalgia and projected pain). The mechanism of referred otalgia involves several non adjacent nerve territories as those of head, neck or ear. Referred otalgia is a projected pain due to ...


Surgery With or Without Adjuvant Stereotactic Body Radiotherapy

The primary objective of this study is to compare the 1-year local control in patients with operable, recurrent previously-irradiated squamous cell head-and-neck cancers with or without adjuvant SBRT. The secondary objectives of this study are to determine the locoregional progression-free survival (PFS) distant PFS, overall PFS (local + regional + ...

Phase N/A

Multimodal Imaging for Surveillance of Patients With Oral Potentially Malignant Disorders

Study Visits: While you are on study, you will have about 4 study visits during an already scheduled, routine clinic visit. Each visit will last about 20-25 minutes total. During each visit, you will have your mouth examined and imaged and you will have brush and tissue biopsies to check ...

Phase N/A

Prospective Registration of Head and Neck Cancer

Review of medical records Medical records of enrolled patients will be reviewed to evaluate clinical characteristics, treatment-related adverse events, time to progression and overall survival. Behavioral : Questionnaires 3 times : Prior to the 1 week before treatment(radiotherapy or chemotherapy) begins or been hospitalized for surgery the same day, 1 ...

Phase N/A

Comparative Study of Robot BABA Approach and Chest Breast Approach for Lateral Neck Dissection

To compare the difference of operative time and complication between two operative methods in robot neck surgery and routine endoscopic surgery.

Phase N/A

Provider Training in Increasing Patient Tobacco Cessation Counseling and Referrals for Patients With Cancer Undergoing Radiation Therapy

PRIMARY OBJECTIVES: I. To determine if training providers on tobacco cessation resources increases the frequency of counseling and referrals at initial and follow-up consultations for cancer patients who use tobacco and are scheduled to receive radiation at Oregon Health and Science University (OHSU). SECONDARY OBJECTIVES: I. Increase provider frequency of ...

Phase N/A