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Head and Neck Cancer Clinical Trials

A listing of Head and Neck Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (33) clinical trials

Prospective Non-interventional Post-authorization Safety Study That Includes All Patients Diagnosed as Unresectable Differentiated Thyroid Carcinoma and Treated With Sorafenib

This is a non-interventional, multi center post-authorization safety study that includes all patients diagnosed as Unresectable Differentiated Thyroid Carcinoma (DTC) and treated with Sorafenib within a certain period. The investigator should have made the choice of treatment (NEXAVAR) according with the Japanese Package Insert prior to enrolling the patient in ...

Phase N/A

An Observational Study in Differentiated Thyroid Cancer Which is Radioactive Iodine (RAI) Refractory to Assess the Use of Multikinase Inhibitors

The primary objective of this study is to compare time to symptomatic progression (TTSP) from study entry in asymptomatic patients with RAI-refractory progressive DTC for whom there is a decision to initiate MKIs at study entry with that of asymptomatic patients with RAI-refractory progressive DTC for whom there is a ...

Phase N/A

Post-marketing Surveillance of Lenvatinib Mesylate (Lenvima Capsule) in Patients With Unresectable Thyroid Cancer (Study LEN01T)

This study is a post-marketing surveillance of lenvatinib in participants with unresectable thyroid cancer. The objectives of this study are to capture unknown adverse reactions, incidences of adverse drug reaction, efficacy, factors considered to have effect to safety and effectiveness, and incidences of hypertension, hemorrhagic events and thromboembolic event, and ...

Phase N/A

ctDNA in Patients With Thyroid Nodules

After the participants with thyroid nodules or other abnormalities have undergone the informed consent process, they will have 30 milliliters (approximately two tablespoons) of blood drawn. This will be done prior to the performance of the fine needle aspiration biopsy of the thyroid. If the patient has indicated a desire ...

Phase N/A

International Nutrition Audit in FORegut TuMors

The proposed project is a prospective inception cohort study of current nutrition practices of patients with foregut tumors (esophageal and/or head & neck cancer) in cancer care settings in Canada, Europe and Australia. This multi center study will involve a baseline audit of current nutrition practice, followed by repeated audit ...

Phase N/A

Quantitative Optical Sensor Findings in Head & Neck Squamous Cell Carcinoma

PURPOSE OF THE STUDY: HYPOTHESES: Noninvasive optical spectroscopic measurements of Head and Neck Squamous Cell Carcinoma (HNSCC) result in unique signatures that can differentiate between dysplasia, normal, other benign conditions as well as response to radiation therapy as assessed by clinical and histopathological methods. STUDY OBJECTIVES 1. Characterization of physiological ...

Phase N/A

DNA Analysis of Tumor Tissue Samples From Patients With Human Papilloma Virus-Associated Cancer of the Oropharynx

OBJECTIVES: - Analyze PIK3CA expression and mutation and p110α amplification and expression in tumor tissue samples from patients with human papilloma virus positive (HPV+) and human papilloma virus negative (HPV-) squamous cell carcinoma (SCC) of the oropharynx. - Determine proliferation and survival after PI3K inhibition in HPV(+) and HPV(-) oropharyngeal ...

Phase N/A

Markers for Cancer in Families at High Risk of Nasopharyngeal Cancer

OBJECTIVES: - Evaluate the clinical utility of serum Epstein-Barr virus antibody testing for the identification of individuals at increased risk of nasopharyngeal carcinoma (NPC) within high-risk NPC multiplex families. OUTLINE: Participants undergo ear, nose, and throat examination (i.e., collection of blood, saliva, nasopharyngeal tissue, and urine and undergo a nasopharyngeal ...

Phase N/A

Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants

OBJECTIVES: - Maintain and update a clinical database pertaining to diagnosis and treatment outcome of patients with head and neck cancer. - Develop a repository of biospecimens from these patients. OUTLINE: Tumor tissue samples and/or bronchial washings are collected from patients undergoing planned surgery and/or bronchoscopy, respectively. Buccal swabs and/or ...

Phase N/A

Biomarkers in Tissue Samples From Patients Who Have Undergone Neck Dissection for Oral Cancer

OBJECTIVES: - To test preliminary data from node-positive oral squamous cell carcinoma (OSCC) signatures for their ability to predict lymph-positive primaries using a cohort of OSCC tumors. - To perform lymph node prediction using sentinel lymph node-biopsied primaries. - To validate the preliminary data node-positive OSCC signature and test its ...

Phase N/A