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Asthma Clinical Trials

A listing of Asthma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (7) clinical trials

A Study to Investigate Safety Tolerability Pharmacokinetics and Pharmacodynamics of Single Dose in Healthy Volunteers Repeat Doses in Asthmatic Patients and of Single Dose in COPD Patients of CHF6366

CHF6366 is a novel bifunctional compound displaying both muscarinic receptor antagonist and 2-adrenergic receptor agonist properties (MABA), with the potential to deliver optimal bronchodilation after inhalation dosing via two validated mechanisms in one molecule. The study will consist of three parts: Part 1 will consit of two cohorts of healthy ...


Bronchial Thermoplasty for Severe Asthmatics Guided by HXe MRI

This study explores the feasibility of using hyperpolarized xenon (HXe) Magnetic Resonance Imaging (MRI) as a diagnostic imaging agent to prioritize the order of airway treatment by bronchial thermoplasty, rather than the FDA approved pre-established treatment sequence that is performed today. The Alair Bronchial Thermoplasty System is an FDA approved ...


Effect of Bronchial Thermoplasty on Moderate Bronchial Asthma in China

This is a multi-center, open-label and single arm study. At least 50 patients with moderate asthma receive Bronchial Thermoplasty for three times. Asthma Quality of Life Questionnaire (AQLQ), Asthma Control Questionnaire (ACQ), Frequency of mild asthma acute attack, PEF, FEV1, Emergency and Hospitalization are compared between before and after BT ...


Mentored Patient-Oriented Research Career Development Award

Asthmatics have inflammation in the large airways (tubes through which air travels in and out of the lungs). The large airways are located in the central lung. New research shows that asthmatics also have inflammation in the small airways. The small airways are located in the peripheral lung (the parts ...


Treatment of Bronchial Asthma With Borage and Echium Seed Oils

Leukotrienes are important in the pathogenesis of inflammation, and leukotriene modifying drugs are now an established treatment for bronchial asthma and rhinitis. Drugs that inhibit the biosynthesis of leukotrienes are likely to be more effective than the currently available drugs that antagonize a single leukotriene receptor. Dietary supplementation with gamma ...


Increased Lung Volume as Controller Therapy for Asthma

The effect of 10 versus 0 cmH2O PEEP on airways responsiveness to inhaled methacholine will be studied using an adaptive "3+3" phase I/II study design. Dose Titration Phase (phase I): The efficacy of 8 hours of PEEP on airway responsiveness will be tested in three subjects. Efficacy will be defined ...


PEEP as Rescue Therapy for Asthmatics With Elevated BMI

This study will investigate whether PEEP can prevent and/or reverse bronchoconstriction in asthmatics with a BMI > 35 kg/m2. People with late-onset non-allergic asthma that develops in the setting of obesity do not respond well to conventional asthma medications, likely because all treatments for asthma have been developed to treat ...