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Sepsis and Septicemia Clinical Trials

A listing of Sepsis and Septicemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (192) clinical trials

National Study on Listeriosis and Listeria

Context: Listeriosis is a foodborne infection responsible for severe disease. Surveillance of human listeriosis in France is based on both mandatory reporting of cases and voluntary submission of L. monocytogenes strains to the National Reference Center for Listeria (NRC) since 1999. The exhaustiveness of this reporting estimated by capture-recapture is ...

Phase N/A

Release of Nociceptin From Granulocytes in Sepsis

Nociceptin is a protein found in the body, with a number of functions in the central nervous system, blood vessels and the gut. There is evidence that it may have a role in controlling the immune response to infection, and may act as a link between the brain and immune ...

Phase N/A

Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis

The patient will be followed during their ICU stay up to two weeks while on mechanical ventilation. Patient will be followed daily for the initial 48 hours and then once per week for 2 weeks while mechanically ventilated.

Phase N/A

Personalised Medicine With Pentaglobin Compared With Standard of Care for Treatment of Peritonitis After Infectious Source Control

The purpose of this study is to test the adjuvant IgGAM treatment for: An improvement of the outcome for the patient's peritonitis. This will be investigated by using scores such as the multiple organ failure and SOFA scores as well as survival data. Identification of biomarkers (Ig level, PCT, IL ...


Severe Sepsis and Septic Shock Registry

This registry prospectively enrolls adult patients with severe sepsis or septic shock in 21 tertiary hospital emergency departments. Registered data can be used for quality control and clinical research to reduce sepsis-related mortality.

Phase N/A

Repository for Sepsis and Postresuscitation Samples

The objective of this study is to find a new therapeutic strategy by investigating the serial serum samples of patients with sepsis or postresuscitation state.

Phase N/A

Role of Active Deresuscitation After Resuscitation-2

The optimal approach to fluid balance in critically ill patients is uncertain. A recent systematic review found low quality evidence in favour of a conservative fluid or deresuscitative approach (active removal of accumulated fluid using diuretics and/or renal replacement therapy) compared with a liberal strategy or usual care. The RADAR-2 ...

Phase N/A

Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients

To Assess Safety, Tolerance, Pharmacokinetics, Pharmacodynamic of multiple-dose Kukoamine B Mesilate in Sepsis Patients


Clinical Microbial Species and Antibiotic Resistance Identification in Patients Presenting to the Emergency Department With Three of Four Systemic Inflammatory Response Syndrome (SIRS) Criteria - is Rapid Identification Possible and Accurate?

Dramatic improvement in the timely and effective treatment of patients afflicted with sepsis can be achieved with the implementation of modern technologies for identification of offending microbial species and their innate genetic antibiotic treatment targets. Our collaborative team is planning to address this need using a Point-of-Care (POC) device equipped ...

Phase N/A

Dysfunctions of Human Muscle Stem Cells in Sepsis

Severe critical illness is often complicated by Intensive Care Unit - Acquired Weakness (ICU-AW), which is clinically characterized by bilateral and symmetrical limb weakness and is related to a myopathy and/or axonal polyneuropathy. ICU-AW affects between 25% to 60% mechanically ventilated patients more than 7 days and is associated with ...

Phase N/A