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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (152) clinical trials

People with Parkinson's Disease are asked to participate in a research study being conducted by New York University School of Medicine.

Phase N/A

Effectiveness of study drug  LY3154207 on cognition and memory in person's with Mild to Moderate Parkinson's Disease Dementia (PDD)

Phase

This is a Phase 3, 12-week, multi-Center, multi-national, randomized, double-blind, double-dummy, parallel-group study to determine the effectiveness, safety and tolerability of P2B001 taken once daily compared to its individual components in adults with early Parkinson's disease (PD) and to a calibration arm of Pramipexole ER. A total of 525 eligible ...

Phase

This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of GZ/SAR402671 in patients with early-stage Parkinson’s disease carrying a GBA mutation or other prespecified variant. The total study duration per subject in Part 2 will be approximately 168 weeks that will consist of 6.5 weeks ...

Phase

This study will assess the effectiveness of pimavanserin when given along with a selective serotonin reuptake inhibitor/selective norepinephrine reuptake inhibitor (SSRI/SNRI) for depression in adults with Parkinson’s disease.

Phase

This is a phase 1, multicenter, single-ascending dose study to evaluate the safety, tolerability, and pharmacokinetics of a study drug (CERC-301) in adults with symptomatic Neurogenic Orthostatic Hypotension (nOH) associated with Parkinson's disease (PD).

Phase

This is a phase 2a, multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety, pharmacokinetics, and pharmacodynamics of a study drug (BIIB054) in adults with Parkinson’s disease (PD).

Phase

This is a multi-site, placebo-controlled, double-blind, randomized-withdrawal study evaluating the durability of clinical benefit of a study drug for patients with symptomatic neurogenic orthostatic hypotension. This study has a duration of up to 36 weeks, consisting of 5 periods:  Screening Period: up to 4 weeks duration;  Open-Label Titration Period (Titration ...

Phase

People with Parkinson's Disease Dementia are asked to participate in a research study being conducted by New York University School of Medicine.

Compensation Mechanisms in Parkinson's Disease

Parkinson's disease onset is clinically defined as the appearance of motor symptoms including akinesia, tremor and hypertonia. Several studies have shown that motor symptoms occur when at least 50 % of dopaminergic neurons are lost. However, there are evidence suggesting that the level of dopaminergic denervation is not homogenous at ...

Phase N/A