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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (130) clinical trials

This study is a 4-week, multicenter, randomized, double-blind, placebo-controlled, ascending dose, 4-period crossover study designed to evaluate the safety, tolerability, efficacy, and PK of JZP-110 (75, 150, and 300 mg) in the treatment of excessive sleepiness in adult subjects with idiopathic PD. *Montefiore Sleep-Wake Disorders Center*

Phase

Dr. Kevin Black will look at the safety and effectiveness of an investigational drug compared to placebo (inactive substance) in the treatment of Parkinson’s disease with psychosis. Participation in this study may last up to 12 weeks. There will be a screening visit lasting about 3 hours and up to ...

Phase

Parkinson’s disease (PD) affects millions of people all over the world. Dealing with it may seem daunting and frustrating. Medications can help manage some of the symptoms like the shaking and jerking, but over time they may not seem to work as well. We’re conducting a study of an investigational ...

Phase N/A

Dr. Brad Racette will look at an investigational inhaler method for taking medication for Parkinson’s disease (PD). There are up to 7 outpatient office visits that will take 1 to 5 hours each. Participants will receive study drug or a placebo by an inhaler. Compensation is provided. Risks and benefits ...

Phase

People with Parkinson’s disease are asked to participate in a research study being conducted by New York University School of Medicine.

Phase N/A

The purpose of this study is to see if selegiline and tadalafil (generic for Cialis®) results in an improvement in Erectile dysfunction (ED) in male patients with Parkinson's disease (PD) and moderate ED. Male PD patients who have an incomplete response to tadalafil alone will be given both medications to ...

Phase

A Phase 1B, 2-Period, Open Label, Multicenter, Dose Escalation study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of PF-06649751 in subjects with Parkinson’s disease and motor fluctuations.

Phase N/A

The study will involve an eighteen-week, double-blind, placebo-controlled parallel designed comparison between add-on topiramate and add-on placebo to stable treatment with amatadine in the treatment of PD patients who continue to have dyskinesia on amantadine.

Phase

This is a prospective, multi-center, randomized, double-blind, placebo-controlled, Phase 3 study in L-Dopa responsive Parkinson's disease patients with motor fluctuations (or "OFF" episodes), designed to determine the efficacy, safety and tolerability of APL-130277 (the study drug). APL-130277 is a fast-acting thin film formulation of apomorphine (APOKYN®) that is placed under ...

Phase

This study is a randomized 1:1 placebo-controlled 10-week study of Mirabegron as add-on therapy to an educational intervention of behavioral modification including pelvic floor exercise (PFE) in a cohort of 40 Parkinson's subjects over the age of 30 with overactive bladder (OAB). Active drug will be Mirabegron 25 mg daily ...

Phase