Narrow Band Imaging Versus White Light for Colonoscopy Serrate Lesions Detection

Last updated: September 25, 2018
Sponsor: Hospital Beatriz Ângelo
Overall Status: Active - Recruiting

Phase

N/A

Condition

Colon Cancer

Treatment

N/A

Clinical Study ID

NCT02876133
176
  • Ages 40-80
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

Colorectal cancer (CRC) is a leading cause of cancer death and its' incidence is rising in most European countries. Colonoscopy has been shown to reduce CRC incidence, however its effectiveness depends on the sensitivity to detect pre-malignant lesions.

Our aim is to evaluate narrow band imaging (NBI) during colonoscopy and serum miRNAs as novel tools for the early detection of colonic sessile serrated lesions (SSL). The investigators will perform a multicenter-randomized-controlled-trial to study the role of NBI in SSL detection.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Patients scheduled for elective colonoscopies

Exclusion

Exclusion Criteria:

  • known polyposis syndromes

  • primary sclerosing cholangitis

  • inflammatory bowel disease

  • personal colorectal cancer history

Study Design

Total Participants: 987
Study Start date:
November 01, 2016
Estimated Completion Date:
August 31, 2019

Connect with a study center

  • Hospital Beatriz Ângelo

    Loures,
    Portugal

    Active - Recruiting

  • Centro Hospitalar do Porto

    Porto,
    Portugal

    Site Not Available

  • Instituto Português de Oncologia do Porto

    Porto,
    Portugal

    Site Not Available

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