Last updated on March 2018

A Study to Evaluate the Onset of Effect and Time Course of Change in Lung Function With Benralizumab in Severe Uncontrolled Asthma Patients With Eosinophilic Inflammation


Brief description of study

The purpose of this study is to investigate the onset and maintenance of effect of benralizumab on lung function, blood eosinophils, asthma control metrics and quality of life during 12-week treatment in patients with uncontrolled, severe asthma with eosinophilic inflammation. A subset of patients will take part in body plethysmography substudy to further investigate the effect on lung function.

Clinical Study Identifier: NCT02869438

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Scottsboro, AL United States

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Denver, CO United States

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Miami, FL United States

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Tampa, FL United States

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Vero Beach, FL United States

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Winter Park, FL United States

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Decatur, GA United States

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Fort Mitchell, KY United States

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Rochester, MN United States

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New Brunswick, NJ United States

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New Bern, NC United States

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Cincinnati, OH United States

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Oklahoma City, OK United States

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Medford, OR United States

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Philadelphia, PA United States

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Lampasas, TX United States

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McKinney, TX United States

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Curico, Chile

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Santiago, Chile

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Bamberg, Germany

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Darmstadt, Germany

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Frankfurt am Main, Germany

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Frankfurt, Germany

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Hamburg, Germany

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Hannover, Germany

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Mainz, Germany

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Balassagyarmat, Hungary

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Gilbert, AZ United States

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Anderson, SC United States

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München, Germany

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Edelény, Hungary

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Farkasgyepü, Hungary