Last updated on May 2018

Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention


Brief description of study

There are insufficient data on the safety and efficacy of edoxaban plus antiplatelet therapy in subjects with atrial fibrillation AF following percutaneous intervention PCI with stenting. This study is designed to evaluate the safety and to explore the efficacy of an edoxaban-based antithrombotic regimen versus a vitamin K antagonist VKA-based antithrombotic regimen in subjects with AF following PCI with stent placement. Bleeding is a central safety outcome in cardiovascular clinical trials, especially for antithrombotic strategies and invasive procedures.

Clinical Study Identifier: NCT02866175

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Study Coordinator

Medizinische Universitaetsklinik Graz
Graz, Austria
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Principal Investigator

University Hospital Innsbruck
Innsbruck, Austria
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Kepler Universitaetsklinikum
Linz, Austria
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Krankenhaus Hietzing
Wien, Austria
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Wilhelminenspital
Wien, Austria
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Study Coordinator

ASZ Aalst
Aalst, Belgium
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Study Coordinator

Imelda Ziekenhuis
Bonheiden, Belgium
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AZ St Jan
Brugge, Belgium
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Hopital Erasme
Brussel, Belgium
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Study Coordinator

University Hospital Antwerp
Edegem, Belgium
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Virga Jesse Jessa hospital
Hasselt, Belgium
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AZ Delta
Roeselare, Belgium
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University Hospital of Angers
Angers, France
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Hopital Cote Basque
Bayonne, France
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Chru Jean Minjoz
Besancon, France
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Metropole Savoie Hospital
Chambery, France
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Centre Hospitalier Sud Francilien
Corbeil Essonnes Cedex, France
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Hospital Henri Mondor
Creteil, France
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CHU Francois Mitterrand
Dijon, France
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CHRU de Lille ICP-Cardiologie
Lille, France
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H pital Cardiovasculaire Louis Pradel
Lyon, France
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Clinique du MILLENAIRE
Montpellier, France
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CHU de Nice
Nice, France
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Groupe Hospitalo-Universitaire Caremeau
Nimes, France
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H pital Bichat - Claude Bernard
Paris cedex 8, France
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Pitie Salpetriere Hospital - Cardiology
Paris, France
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Groupe Hospitalier Sud
Pessac, France
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H pital Pontchailloux-CHU
Rennes, France
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Clinique Saint Hilaire
Rouen, France
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Laura Strong

H pital Rangueil, Service canc rologie
Toulouse, France
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Centre Hospitalier de Valenciennes
Valenciennes, France
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Clinique Vauban
Valenciennes, France
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University Hospital Aachen
Aachen, Germany
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Universit ts-Herzzentrum Freiburg Bad Krozingen
Bad Krozingen, Germany
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Kerckhoff Klinik
Bad Nauheim, Germany
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Vivantes Klinikum im Friedrichshaim
Berlin, Germany
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Vivantes Klinikum am Urban Kardiologie, Allgemeine Innere Medizin und Konservative Intensivmedizin
Berlin, Germany
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Charit Benjamin Franklin
Berlin, Germany
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Charit , Campus Virchow-Klinikum - Medizinische Klinik mit Schwerpunkt Kardiologie
Berlin, Germany
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Staedtische Kliniken Bielefeld
Bielefeld, Germany
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GFO Kliniken Bonn - St.-Marien-Hospital
Bonn, Germany
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Universit tsklinikum Bonn - Medizinische Klinik II - Innere Medizin (Kardiologie, Angiologie und Pneumologie)
Bonn, Germany
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Klinikum Coburg Med. Klinik Kardiologie, Angiologie, Pneumologie
Coburg, Germany
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St. Johannes- Hospital
Dortmund, Germany
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Universitaetsklinikum Freiburg Klinik f r Kardiologie und Angiologie I
Freiburg, Germany
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Klinikum Fulda AG
Fulda, Germany
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Universit res Herzzentrum Hamburg GmbH (UHZ)
Hamburg, Germany
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Universit tsklinikum Heidelberg Klinik f r Kardiologie, Angiologie und Pneumologie (Innere Medizin III)
Heidelberg, Germany
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Universit tsklinikum des Saarlandes Innere Medizin III - Kardiologie, Angiologie und internistische Intensivmedizin
Homburg, Germany
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Universit tsklinikum Jena Klinik f r Innere Medizin I, Kardiologie, Angiologie, Pneumologie, Internistische Intensivmedizin
Jena, Germany
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Herzzentrum Leipzig - Universit tsklinik Klinik f r Innere Medizin/Kardiologie
Leipzig, Germany
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Klinikum Ludwigshafen
Ludwigshafen, Germany
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Universit tsmedizin Mannheim
Mannheim, Germany
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Johannes Wesling Klinikum Minden, Cardiology
Minden, Germany
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St. Vincenz-Krankenhaus Paderborn - Medizinische Klinik II
Paderborn, Germany
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University Hospital Regensburg
Regensburg, Germany
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Herzklinik Ulm
Ulm, Germany
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Universit tsklinik Ulm - Zentrum f r Innere Medizin - Klinik f r Innere Medizin II
Ulm, Germany
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Schwarzwald-Baar Klinikum - Kliniken Villingen-Schwenningen - Innere Medizin III: Kardiologie und Intensivmedizin
Villingen-Schwenningen, Germany
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St. Josefs-Hospital - Medizinische Klinik I, Kardiologie
Wiesbaden, Germany
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HELIOS Klinikum Wuppertal - Herzzentrum
Wuppertal, Germany
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Budai Irgalmasrendi Kht.
Budapest, Hungary
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Gottsegen Gy rgy Orsz gos Kardiol giai Int zet
Budapest, Hungary
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Bajcsy-Zsilinszky K rh z s Rendel int zet
Budapest, Hungary
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Magyar Honv ds g Eg szs g gyi K zpont
Budapest, Hungary
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Debreceni Egyetem Klinikai K zpont
Debrecen, Hungary
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B k s Megyei K zponti K rh z
Gyula, Hungary
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H pital Rangueil, Service Canc rologie
Toulouse, France
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Universit tsmedizin Rostock
Rostock, Germany
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Heinrich-Heine-Universit t D sseldorf - Universit tsklinikum D sseldorf (UKD) Klinik f r Kardiologie, Pneumologie und Angiologie
Düsseldorf, Germany
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St dtisches Klinikum L neburg
Lüneburg, Germany
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Kliniken Maria Hilf GmbH
Mönchengladbach, Germany
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Klinik Dr. M ller GmbH & Co. KG, Peter Osypka Herzzentrum
München, Germany
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Universit tsklinikum M nster - Department f r Kardiologie und Angiologie
Münster, Germany
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Universit ts Klinikum T bingen
Tübingen, Germany
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llami Sz vk rh z
Balatonfüred, Hungary
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