Last updated on October 2017

Tepotinib Phase II in NSCLC Harbouring MET Exon 14 (METex14) Skipping Alterations


Brief description of study

This study will look at how effective the study drug (tepotinib) is at stopping the growth and spread of lung cancer. This study will also measure a number of other things including safety of the study drug and the side effects, how body processes the study drug, or how the study drug affects your quality of life. The study also has an optional pharmacogenetic research part. Pharmacogenetic research is an important way to try to understand the role of genetics in human disease and how genes impact the effectiveness of drugs, because differences in genes can change the way a person responds to a particular drug.

Clinical Study Identifier: NCT02864992

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Ravi Salgia

City of Hope Cancer Center
Duarte, CA United States
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Alberto Bessudo

California Cancer Associates for Research & Excellence, Inc.
Encinitas, CA United States
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Sai-Hong Ou

UCI Medical Center
Orange, CA United States
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Andrew Horodner

Torrance Health Association
Redondo Beach, CA United States
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Robert Jotte

Rocky Mountain Cancer Centers, LLP
Denver, CO United States
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David Drew

Holy Cross Hospital Inc.
Fort Lauderdale, FL United States
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Petros Nikolinakos

University Cancer & Blood Center, LLC
Athens, GA United States
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Conor Steuer

Winship Cancer Institute
Atlanta, GA United States
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Jyoti Patel

University of Chicago Medical Center
Chicago, IL United States
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Mark Kozloff

Ingalls Hospital
Harvey, IL United States
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Rhadika Walling

Community Regional Cancer Care
Indianapolis, IN United States
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Ralph Boccia

Center for Cancer and Blood Disorders
Bethesda, MD United States
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US Medical Information

For Recruiting Locations in the United States, please Contact U.S. Medical Information
Rockland, MA United States
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Juan Cuevas

St. Louis Cancer Care, LLP
Bridgeton, MO United States
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Nishant Poddar

Saint Louis University
Saint Louis, MO United States
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Michael Wax

Summit Medical Group
Berkeley Heights, NJ United States
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Harry Harper

Hackensack University Medical Center PARTNER
Hackensack, NJ United States
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Eli Kirshner

Prospect Medical Offices, LLC
Midland Park, NJ United States
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Paul Paik

Memorial Sloan Kettering Cancer Center
New York, NY United States
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John Morris

UC Health Clinical Trials Office
Cincinnati, OH United States
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Melissa Johnson

Tennessee Oncology
Nashville, TN United States
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Leora Horn

Vanderbilt University Medical Center
Nashville, TN United States
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James Uyeki

Texas Oncology, P.A. - Austin
Austin, TX United States
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Sharon Wilks

Texas Oncology, PA
Beaumont, TX United States
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Kartik Konduri

Texas Oncology, P.A.
Dallas, TX United States
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Alexander Spira

Virginia Cancer Specialists, PC
Fairfax, VA United States
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Howard West

Swedish Medical Center
Seattle, WA United States
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Lindsay Overton

Wenatchee Valley Medical Center Oncology
Wenatchee, WA United States
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Jan Van Meerbeeck

UZ Antwerpen
Edegem, Belgium
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Stephanie Holbrechts

CHU Ambroise Par
Mons, Belgium
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Ingel Demedts

AZ Delta
Roeselare, Belgium
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Remi Veillon

Groupe Hospitalier Sud - H pital Haut-L v que
Pessac, France
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Julien Mazières

CHU de Toulouse - H pital Larrey
Toulouse, France
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Helene Senellart

ICO - Site Ren Gauducheau
Saint Herblain, France
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Thierry Chatellier

Clinique Mutualiste de l'Estuaire
Saint Nazaire Cedex, France
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Helene Senellart

ICO - Site Paul Papin
Angers Cedex 2, France
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Philippe Masson

Centre Hospitalier de Cholet
Cholet, France
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Régine Lamy

Centre Hospitalier de Bretagne Sud
Lorient cedex, France
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Alexis Cortot

Hopital Albert Calmette - CHU Lille
Lille Cedex, France
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Ludovic Doucet

H pital Saint-Louis
Paris Cedex 10, France
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Sophia Schneider

Centre Hospitalier de la c te Basque
Bayonne, France
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Christos Chouaid

Centre Hospitalier Intercommunal de Cr teil
Creteil cedex, France
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Acya Bizieux

Centre Hospitalier D partemental Les Oudairies
La Roche sur Yon, France
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Niels Reinmuth

Asklepios Fachkliniken Muenchen-Gauting
Gauting, Germany
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Thomas Wehler

Universitaetsklinikum des Saarlandes
Homburg / Saar, Germany
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Stefan Hammerschmidt

Klinikum Chemnitz gGmbH
Chemnitz, Germany
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Martin Wermke

Universitaetsklinikum Carl Gustav Carus TU Dresden
Dresden, Germany
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Christian Gessner

POIS Leipzig GbR
Leipzig, Germany
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Bernd Mross

Helios Klinikum Erfurt
Erfurt, Germany
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Sebastian Ochsenreither

Charite Universitaetsmedizin Berlin - Campus Charite Mitte
Berlin, Germany
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US Medical Information

For Recruiting Locations outside US, please Contact Merck KGaA Communication Center
Darmstadt, Germany
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Clelia Casartelli

Ospedale Valduce
Como, Italy
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Francesco Grossi

Istituto Nazionale per la Ricerca sul Cancro di Genova
Genova, Italy
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Marina Garassino

Fondazione IRCCS Istituto Nazionale dei Tumori
Milano, Italy
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Filippo de Marinis

IEO Istituto Europeo di Oncologia
Milano, Italy
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Fortunato Ciardiello

Seconda Universit degli Studi di Napoli
Napoli, Italy
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Giuseppe Tonini

Universit Campus Bio-Medico di Roma
Roma, Italy
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Maria Rita Migliorino

Azienda Ospedaliera San Camillo Forlanini
Roma, Italy
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Masahiro Morise

Nagoya University Hospital
Nagoya-shi, Japan
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Shingo Matsumoto

National Cancer Center Hospital East
Kashiwa-shi, Japan
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Toshiyuki Kozuki

NHO Shikoku Cancer Center
Matsuyama-shi, Japan
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Masao Ichiki

NHO Kyushu Medical Center
Fukuoka-shi, Japan
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Kazuhiko Yamada

Kurume University Hospital
Kurume-shi, Japan
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Naofumi Shinagawa

Hokkaido University Hospital
Sapporo-shi, Japan
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Terufumi Kato

Kanagawa Cancer Center
Yokohama-shi, Japan
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Hiroshi Tanaka

Niigata Cancer Center Hospital
Niigata-shi, Japan
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Fumio Imamura

Osaka International Cancer Institute
Osaka-shi, Japan
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Shinji Atagi

NHO Kinki-Chuo Chest Medical Center
Sakai-shi, Japan
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Hiroshi Sakai

Saitama Cancer Center
Kitaadachi-gun, Japan
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Kenichi Chikamori

NHO Yamaguchi - Ube Medical Center
Ube-shi, Japan
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Wojciech Naumnik

Uniwersytecki Szpital Kliniczny w Bialymstoku
Bialystok, Poland
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Adam Pawlak

Centrum Pulmonologii i Torakochirurgii w Bystrej
Bystra, Poland
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Slawomir Mandziuk

Dr n med. Slawomir Mandziuk Specjalistyczna Praktyka Lekarska
Lublin, Poland
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Malgorzata Suszko-Kazarnowicz

NZOZ Olsztynski Osr. Onkologiczny "Kopernik" Sp.z o.o
Olsztyn, Poland
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Rodryg Ramlau

Przychodnia Med-Polonia Sp. z o.o.
Poznan, Poland
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Dariusz Kowalski

Centrum Onkologii-Instytut im. M. Sklodowskiej Curie
Warszawa, Poland
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Irene Moya Horno

Hospital General de Catalunya
Sant Cugat del Valles, Spain
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Inmaculada Fernandez Canton

Hospital de Especialidades de Jerez de la Frontera
Jerez de la Frontera, Spain
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Cristobal Belda Iniesta

Hospital Universitario HM Puerta del Sur
Mostoles, Spain
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Maria Sereno Moyano

Hospital Universitario Infanta Sofia
San Sebastian de los Reyes, Spain
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Edith Rodriguez Braun

Hospital General Universitario Santa Lucia
Cartagena, Spain
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Jose Manuel Trigo Perez

Hospital Clinico Universitario Virgen de la Victoria
Malaga, Spain
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Santiago Viteri Ramirez

Hospital Universitari Quiron Dexeus
Barcelona, Spain
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Niki Karachaliou

Hospital Universitari Sagrat Cor
Barcelona, Spain
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Enriqueta Felip Font

Hospital Universitari Vall d'Hebron
Barcelona, Spain
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Rosa Alvarez Alvarez

Hospital General Universitario Gregorio Mara on
Madrid, Spain
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Pilar Lopez Criado

MD Anderson Cancer Centre
Madrid, Spain
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Luis Paz-Ares Rodriguez

Hospital Universitario 12 de Octubre
Madrid, Spain
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Javier de Castro Carpeño

Hospital Universitario La Paz
Madrid, Spain
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Javier de Castro Carpeño

Hospital Universitario HM Madrid Sanchinarro
Madrid, Spain
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David Vicente Baz

Hospital Universitario Virgen Macarena
Sevilla, Spain
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Jose Fuentes Pradera

Hospital Universitario Nuestra Se ora de Valme
Sevilla, Spain
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