Last updated on February 2018

Study of Pembrolizumab (MK-3475) Monotherapy in Locally Advanced/Metastatic Renal Cell Carcinoma (MK-3475-427/KEYNOTE-427)


Brief description of study

The purpose of this study is to assess the safety and efficacy of monotherapy pembrolizumab (MK-3475) in participants with renal cell carcinoma (RCC). There will be two cohorts in this study: Cohort A will consist of participants with clear cell (cc) RCC and Cohort B will consist of participants with non-clear cell (ncc) RCC.

Clinical Study Identifier: NCT02853344

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Tucson, AZ United States

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Miami, FL United States

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Chicago, IL United States

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New Orleans, LA United States

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Boston, MA United States

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Detroit, MI United States

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Billings, MT United States

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Las Vegas, NV United States

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New York, NY United States

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Philadelphia, PA United States

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Charleston, SC United States

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Chattanooga, TN United States

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Burlington, VT United States

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Roanoke, VA United States

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Kennewick, WA United States

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Seattle, WA United States

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Milwaukee, WI United States

Thomas Johansson

MSD SRO Czech
Prague, Czechia

Nathan Lassota

Merck Sharp & Dohme
Glostrup, Denmark

Jongho Ahn

MSD Korea LTD
Seoul, Korea, Republic of

Thomas Johansson

MSD Polska Sp. Z o.o.
Warsaw, Poland

Tatiana Serebriakova

Merck Sharp & Dohme IDEA, Inc.
Moscow, Russian Federation

Joaquin Mateos Chacon

Merck Sharp and Dohme de Espana S.A.
Madrid, Spain

Mark Toms

Merck Sharp & Dohme Ltd.
Hoddesdon, United Kingdom

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San Francisco, CA United States

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Washington, WA United States

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Washington, WA United States