Last updated on October 2016

Fluid Responsiveness Evaluation in Sepsis-associated Hypotension


Brief description of study

This study assesses the mean difference in fluid balance at ICU discharge and associated patient outcomes, based on a dynamic assessment of fluid responsiveness in septic patients with refractory hypotension in an ICU setting.

Detailed Study Description

Multi-center randomized study comparing dynamic assessment of fluid responsiveness utilizing Starling SV monitor compared to a control group. Subjects will be randomized in a 2:1 treatment to control group ratio to increase power for sub-analysis by patient population. Patients randomized to the Starling SV arm will have treatment guided by a dynamic assessment of fluid responsiveness (measured by a change in stroke volume index > 10%) as assessed by passive leg raise (PLR). Patients randomized to the control group will receive standard of care treatment.

Clinical Study Identifier: NCT02837731

.

Contact Investigators or Research Sites near you

Start Over

Please choose location

View all locations

Ivor Douglas, MD

Denver Health
Denver, CO United States
  Connect »

Philip Alapat, MD

Baylor College of Medicine
Houston, TX United States
  Connect »