Last updated on February 2017

Effects of Enteral Glutamine Supplementation on Mortality and Infectious Morbidity in Severely Burned Patients: a Multi-center Pilot Trial


Brief description of study

Effects of Enteral Glutamine Supplementation on Mortality and Infectious Morbidity in Severely Burned Patients: a Multi-center Pilot Trial

Detailed Study Description

Enteral glutamine has been found to decrease mortality in critically ill patients and blood infection in trauma patients.
In our pilot study (Critical Care Medicine, 2003, 31:2444) we found the same protective effect of glutamine against blood infection in severely burned adult patients. In addition, a significant decrease in mortality was observed with glutamine. These results should be tested with a multi-center trial because our study was small and did not have mortality as an end point. Since such a large multi center study has never been conducted in burn patients, a pilot study that will test its feasibility seems warranted.

Clinical Study Identifier: TX9262

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Rachel Karlnoski

University of South Florida - Tampa General Hospital
Tampa, FL USA
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