Last updated on February 2018

Use of 31P MRS to Assess Brain NAD+ in Healthy Collegiate Athletes


Brief description of study

Can nicotinamide riboside (750 mg/day for 12 weeks) affect the levels of NAD+ in the brain as measured by 31P MRS?

Detailed Study Description

Healthy collegiate athletes (football, soccer, rugby, hockey, and volleyball) will take Nicotinamide Riboside (NR) or placebo twice daily for 84 days. Pre- and post-intervention evaluations include physical assessment, blood tests for safety and toxicity monitoring, blood tests for biomarkers, neurologic testing, quality of life questionnaires, and the 31P MRI exam.

Clinical Study Identifier: NCT02721537

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Xiao-Hong Zhu, Ph.D.

University of Minnesota Center for Magnetic Resonance Research
Minneapolis, MN United States
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Brent A Bauer, MD

Mayo Clinic
Rochester, MN United States
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