Last updated on May 2018

A Study Evaluating Safety Pharmacokinetics and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)


Brief description of study

This first-in-human, open-label, multicenter, Phase Ia/Ib, adaptive, multiple ascending-dose study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary anti-tumor activity of RO6874281 as a single agent (Part A) or in combination with trastuzumab or cetuximab (Part B or C).

Clinical Study Identifier: NCT02627274

Contact Investigators or Research Sites near you

Start Over

Reference Study ID Number: BP29842 ...

University of Arizona Cancer Center
Tucson, AZ United States
  Connect »

Reference Study ID Number: BP29842 ...

UCSD - Moores Cancer Center
La Jolla, CA United States
  Connect »

Reference Study ID Number: BP29842 ...

University of Colorado Hospital - Anschutz Cancer Pavilion
Aurora, CO United States
  Connect »

Reference Study ID Number: BP29842 ...

Memorial Sloan Kettering
New York, NY United States
  Connect »

Reference Study ID Number: BP29842 ...

Centre Georges Francois Leclerc
Dijon, France
  Connect »

Reference Study ID Number: BP29842 ...

Institut Claudius Regaud; Departement Oncologie Medicale
Toulouse, France
  Connect »

Reference Study ID Number: BP29842 ...

Antoni Van Leeuwenhoek Ziekenhuis; Gastro-Enterologie
Amsterdam, Netherlands
  Connect »

Reference Study ID Number: BP29842 ...

Erasmus MC
Rotterdam, Netherlands
  Connect »

Reference Study ID Number: BP29842 ...

Clinica Universitaria de Navarra
Pamplona, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Hospital del Mar; Servicio de Oncologia
Barcelona, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Hospital Univ Vall d'Hebron; Servicio de Oncologia
Barcelona, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Hospital Universitario 12 de Octubre; Servicio de Oncologia
Madrid, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia
Valencia, Spain
  Connect »

Reference Study ID Number: BP29842 ...

Leicester Royal Infirmary
Leicester, United Kingdom
  Connect »

Reference Study ID Number: BP29842 ...

Barts Health NHS Trust - St Bartholomew's Hospital
London, United Kingdom
  Connect »

Reference Study ID Number: BP29842 ...

Christie Hospital
Manchester, United Kingdom
  Connect »

Reference Study ID Number: BP29842 ...

Fondazione IRCCS Istituto Nazionale dei Tumori;S.S. Trattamento MedicoTumori dellaTesta e delCollo
Milano, Italy
  Connect »

Reference Study ID Number: BP29842 ...

Istituto Europeo di Oncologia; Svil. Nuovi Farmaci per Terapie Innovative
Milano, Italy
  Connect »

Reference Study ID Number: BP29842 ...

Azienda Socio Sanitaria Territoriale Niguarda (Ospedale Niguarda Ca' Granda); Oncologico -Onc.Falck
Milano, Italy
  Connect »

Reference Study ID Number: BP29842 ...

Rigshospitalet, Onkologisk Klinik
København Ø, Denmark
  Connect »