Last updated on November 2017

GUIDE-IT - GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure (GUIDE-IT) -The goal of this US prospective outpatient AF registry is to identify real world treatment patterns in patients with AF(atrial fibrillation), outside of randomized controlled trials. Specifically, the registry will attempt to define current treatment patterns and their relationship with outcomes, including stroke, all-cause mortality, and quality-of-life.


Brief description of study

GUIDE-IT - GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure (GUIDE-IT) -The goal of this US prospective outpatient AF registry is to identify real world treatment patterns in patients with AF(atrial fibrillation), outside of randomized controlled trials. Specifically, the registry will attempt to define current treatment patterns and their relationship with outcomes, including stroke, all-cause mortality, and quality-of-life.

Detailed Study Description

The purpose of this study is to see if using the results of a blood test called NT-proBNP (a hormone released from the heart also known as a biomarker) can help doctors decide the best drug treatment for patients with heart failure (HF). Approximately 1,100 people will take part in this study at approximately 35 different hospitals and medical facilities. The primary endpoint is time to cardiovascular death or first heart failure hospitalization. Once enrolled in the study there is a minimum of 12 months of follow-up.

Clinical Study Identifier: TX81264

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Wendy Schneider, MSN

Holy Cross Jim Moran Heart and Vascular Research Institute
Coral Springs, FL USA
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Cheryl Langer, RN

Holy Cross Jim Moran Heart and Vascular Research Institute
Fort Lauderdale, FL USA
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