Last updated on November 2016

Evaluation of Efficacy and Safety of MEDI2070 in Subjects With Active Moderate to Severe Crohn's Disease


Brief description of study

A Phase 2b study to evaluate the efficacy and safety of MEDI2070 in Subjects with Moderate to Severe Crohn's Disease Who Have Failed or Are Intolerant to Anti Tumor Necrosis Factor-Alpha Therapy

Detailed Study Description

This is a four-part Phase 2b study comprised of a 16-week, double-blind, placebo-controlled, Induction Period, a 12-week double-blind, placebo-controlled, Maintenance Period, a 24-week, Open-label Period and a post-treatment 28 week observational safety follow-up period designed to evaluate the short-term efficacy and the short- and long term safety of MEDI2070 in subjects with moderate to severe, active CD who have failed or are intolerant to anti-TNFα therapy as determined by the Investigator.

Clinical Study Identifier: NCT02574637

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Phoenix, AZ United States
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Garden Grove, CA United States
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Long Tree, CO United States
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Clearwater, FL United States
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Jacksonville, FL United States
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Kissimmee, FL United States
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Miami Springs, FL United States
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Miami, FL United States
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Miramar, FL United States
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Palmetto Bay, FL United States
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Port Orange, FL United States
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Winter Park, FL United States
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Decatur, GA United States
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Macon, GA United States
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Suwanee, GA United States
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Chicago, IL United States
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Evanston, IL United States
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Urbana, IL United States
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Indianapolis, IN United States
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Kansas City, KS United States
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Topeka, KS United States
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Bowling Green, KY United States
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Louisville, KY United States
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Lake Charles, LA United States
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Metairie, LA United States
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Baltimore, MD United States
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Catonsville, MD United States
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Columbia, MD United States
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Ann Arbor, MI United States
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Southfield, MI United States
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Rochester, MN United States
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Belton, MO United States
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Great Neck, NY United States
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New Hyde, NY United States
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New York, NY United States
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Poughkeepsie, NY United States
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Charlotte, NC United States
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Cincinnati, OH United States
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Columbus, OH United States
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Dayton, OH United States
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Portland, OR United States
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Pittsburgh, PA United States
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Sayre, PA United States
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Chattanooga, TN United States
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Nashville, TN United States
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Dallas, TX United States
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Houston, TX United States
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Temple, TX United States
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Seattle, WA United States
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Wauwatosa, WI United States
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Hradec Kralove, Czech Republic
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Valasske Mezirici, Czech Republic
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Saint-Priez en Jarez, France
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Toulouse Cedex 9, France
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Vandoeuvre-Les-Nancy, France
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San Donato Milanese, Italy
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San Giovanni Rotondo, Italy
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Busan, Korea, Republic of
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Daejeon, Korea, Republic of
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Seoul, Korea, Republic of
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Suwon-si, Korea, Republic of
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Wonju-si, Korea, Republic of
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Maastricht, Netherlands
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