Last updated on February 2018

Feasibility Study of Adjuvant Treatment With S-1 in Patients After R0-Resection of Adenocarcinoma of the Stomach and Esophagogastric Junction


Brief description of study

Multicenter trial in Germany:

Feasibility Study of Adjuvant Treatment with S-1 in Patients after R0-Resection of Adenocarcinoma of the Stomach and Esophagogastric Junction with the aim to show the feasibility and tolerability of two different adjuvant S-1 treatment regimens in Caucasian patients and to determine the recommended dose for both treatment regimens.

Detailed Study Description

Patients will be enrolled in two cohorts.

The cohorts 1 an d2 will be conducted consecutively, started with cohort 1. Cohort 1 consists of 30 patients who receive S-1 twice daily for 18 cycles (D1-14 q 3 wks). Cohort 2 consists of 30 patients who receive S-1 twice daily for 9 cycles (D1-28, q 6 wks). Both cohorts will start with 2x 30 mg/m^2 BSA. Two dose reductions will be allowed per protocol.

Clinical Study Identifier: NCT02564367

Contact Investigators or Research Sites near you

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Christoph Schulz, Dr.

Klinikum der Universit t M nchen, Campus Gro hadern
München, Germany
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