Last updated on June 2018

A Multicenter Study to Evaluate the Efficacy and Safety of Cinryze for the Treatment of Acute Antibody-mediated Rejection in Participants With Kidney Transplant


Brief description of study

The main purpose of the study is to evaluate the efficacy of CINRYZE administered with plasmapheresis, plasma exchange, or immune adsorption treatments and sucrose-free immunoglobulin (IVIg) for the treatment of acute antibody-mediated rejection (AMR) of renal allograft in kidney transplant recipients as measured by the proportion of participants with new or worsening transplant glomerulopathy (TG) at 6 months after treatment initiation.

Clinical Study Identifier: NCT02547220

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Suphamai Bunnapradist, MD

Kidney Transplant Research Office at UCLA
Los Angeles, CA United States
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Yasir Qazi, MD

Keck School of Medicine at USC
Los Angeles, CA United States
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Allison Webber, MD

University of California San Francisco
San Francisco, CA United States
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James Cooper

University Of Colorado School Of Medicine
Aurora, CO United States
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Adela Mattiazzi, MD

Jackson Memorial Hospital
Miami, FL United States
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Bobby Nibhanupudy, MD

Florida Hospital Transplant Institute
Orlando, FL United States
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Joshua Wolf

Piedmont Hospital
Atlanta, GA United States
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John Friedewald

Northwestern Memorial Hospital
Chicago, IL United States
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Abdolreza Haririan

University of Maryland Medical Center
Baltimore, MD United States
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Sami Alasfar, MD

Johns Hopkins University
Baltimore, MD United States
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Anil Chandraker, MD

Brigham and Womens Hospital
Boston, MA United States
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Ty Dunn

University of Minnesota
Minneapolis, MN United States
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Daniel Brennan

Washington University School of Medicine
Saint Louis, MO United States
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Anup Patel

Saint Barnabas Medical Center
Livingston, NJ United States
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Nandita Singh, MD

Mount Sinai Hospital
New York, NY United States
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Lloyd Ratner

Columbia University Medical Center
New York, NY United States
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Jim Kim

New York Presbyterian Hospital - Weill-Cornell
New York, NY United States
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Robert Montgomery, MD

NYU Longone Medical Center
White Plains, NY United States
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Ervin Woodle

University of Cincinnati
Cincinnati, OH United States
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Richard Fatica

Cleveland Clinic
Cleveland, OH United States
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Ronald Pelletier

Ohio State University Medical Center
Columbus, OH United States
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Jose El-Amm

INTEGRIS Nazih Zuhdi Transplant Institute
Oklahoma City, OK United States
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Puneet Sood

University of Pittsburgh Medical Center
Monroeville, PA United States
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Roy Bloom, MD

University of Pennsylvania Health System
Philadelphia, PA United States
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Heidi Schaefer

Vanderbilt University Medical Center
Nashville, TN United States
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Bernard Fischbach

Baylor All Saints Medical Center
Fort Worth, TX United States
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Ahmed Gaber

Houston Methodist Hospital
Houston, TX United States
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Fuad Shihab, MD

University of Utah Health Sciences Center
Salt Lake City, UT United States
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John Gill, MD

Providence Health Care Research Institute
Vancouver, BC Canada
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Ruth Sapir-Pichhadze, MD

Royal Victoria Hospital
Montreal, QC Canada
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Gilles Blancho

Hotel Dieu
Nantes, France
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Paolo Malvezzi

CHU Michallon
Grenoble, France
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Denis Glotz

H pital Saint Louis
Paris, France
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Christophe Legendre

Groupe Hospitalier Necker Enfants Malades
Paris, France
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Nassim Kamar

H pital de Rangueil
Toulouse, France
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Claudia Sommerer

Universit t Heidelberg
Heidelberg, Germany
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Ingeborg Hauser

Universit tsklinikum Frankfurt
Steinbach, Germany
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Friedrich Thaiss

Universit tsklinikum Hamburg Eppendorf
Hamburg, Germany
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Jan-Stephan Sanders

Universitair Medisch Centrum Groningen
Groningen, Netherlands
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M.W.F. van den Hoogen

Erasmus MC
Rotterdam, Netherlands
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Ricardo Lauzurica

Hospital Universitario Germans Trias i Pujol
Badalona, Spain
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Oriol Matamoros

Hospital Universitari de Bellvitge
Barcelona, Spain
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Isabel Perez Flores

Hospital Clinico San Carlos
Madrid, Spain
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Amado Andres

Hospital Universitario 12 de Octubre
Madrid, Spain
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Alexander Gilbert

MedStar Georgetown University Hospital
Washington, WA United States
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Philippe Grimbert

Hopital Henri Mondor
Créteil, France
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Antoine Durrbach

Centre Hospitalier Universitaire de Bic tre
Le Kremlin-Bicêtre, France
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